Hepatitis C Disease Detection Based on PCA–SVM Model

Authors : Serdar GÜNDOĞDU

Pages : 111-116

Doi:10.17350/HJSE19030000261

View : 20 | Download : 7

Publication Date : 2022-06-30

Article Type : Research Paper

Abstract :Hepatitis C is a liver disease caused by infection with the hepatitis C virus insert ignore into journalissuearticles values(HCV);, which is transmitted through the blood. The disease can lead to diseases ranging from a mild form to serious lifelong illness. Studies to detect the disease early and reduce its effect are continuing. This study proposes an effective support vector machine model supported by principal component analysis for detecting hepatitis c disease. The dataset consisted of twelve independent variables, each containing 582 samples, and these variables were used as inputs to the two classifiers, support vector machine insert ignore into journalissuearticles values(SVM); and artificial neural network insert ignore into journalissuearticles values(ANN);. The accuracy, sensitivity, specificity, MCC and KAPPA were calculated using two classification models. In addition, performance comparisons of classifiers were made for the two cases with and without PCA insert ignore into journalissuearticles values(principal component analysis); applied to the inputs. The highest accuracy insert ignore into journalissuearticles values(98.7%);, sensitivity insert ignore into journalissuearticles values(99.1%);, specificity insert ignore into journalissuearticles values(95.2%);, MCC insert ignore into journalissuearticles values(92.3%); and Kappa insert ignore into journalissuearticles values(92.3%); in the binary class label were obtained with the SVM with PCA. In the four-class label, the highest accuracy was achieved with the same model with 95.7%. The results show that an SVM classifier model, in which PCA-reduced independent variables are applied to its inputs, may be a candidate for an accurate prediction model to predict hepatitis C disease.
Keywords : ANN, Dimensional reduction, Hepatitis C, PCA, SVM