Evaluation of the Wound Healing Potential of Teucrioside

Authors : Seçil ERDEN TAYHAN, Sema BİLGİN, Mahfuz ELMASTAŞ

Pages : 16-19

Doi:10.32571/ijct.345050

View : 93 | Download : 9

Publication Date : 2018-03-13

Article Type : Research Paper

Abstract :Herbal medicines are being used for primary health care due to their efficacy, safety and less side effects. Teucrium genus is a member of the Lamiaceae family, which is a medicinal plant have been used in traditional medicine, especially for wound healing and inflammatory conditions. Teucroside , 9′-decarboxyrosmarinic acid-4′-O-α-rhamnosyl-insert ignore into journalissuearticles values(1‴→6‴);-O-β-galactosyl-insert ignore into journalissuearticles values(1‴→4″);-O-α-rhamnoside is a natural phenolic compund which is isolated and identified from of Teucrium genus . In this study, because of bioactive properties of Teucrioside , it was decided to examine its potential wound healing effect . Wound healing process was investigated by in vitro scratch assay which was an easy, inexpensive and well developed method to measure cell migration . In this context, firstly, cell viability was determined by MTT assay and the results were evaluated to find effective concentration for wound healing . Then the cells were incubated for 48 h with extract with defined concentration. Finally, after 48 hours of incubation with teucroside , the wound healing was calculated as 47%. When the data were compared with untreated control insert ignore into journalissuearticles values(49%);, it was concluded that teucroside had not wound healing potential.
Keywords : Teucrioside, Lamiaceae, wound healing, scratch assay

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