Comparison of ulnar, median, and sural sensory nerve conduction studies between demyelinating and axonal forms of Guillain-Barré Syndrome

Authors : Mehmet YILDIZ, Halit FİDANCI, Gülçin ORTAÇ, Şencan BUTURAK, Zülfikar ARLIER

Pages : 70-77

Doi:10.47482/acmr.1170798

View : 53 | Download : 64

Publication Date : 2023-05-31

Article Type : Research Paper

Abstract :Background: Guillain-Barré syndrome insert ignore into journalissuearticles values(GBS); is an important neurological disease that can cause disability. Axonal GBS and acute inflammatory demyelinating polyradiculoneuropathy insert ignore into journalissuearticles values(AIDP); are two important subgroups. Methods: Patients with clinical and electrodiagnostic features compatible with GBS were included in this retrospective study. The patients were divided into two groups neurophysiologically as Axonal GBS and AIDP. Medical research council insert ignore into journalissuearticles values(MRC); scores of the patients\` muscles, median / ulnar / posterior tibial / peroneal / sural nerve conduction study findings were included in the analyses. Sural sparing pattern was considered as the absence of median/ulnar compound nerve action potential insert ignore into journalissuearticles values(CNAP); and present sural nerve CNAP insert ignore into journalissuearticles values(SS-M/SS-U);. Results: Twelve AIDP and 10 Axonal GBS patients were included in the study. MRC scores were not different between the two groups insert ignore into journalissuearticles values(p=0.895);. CNAPs of the right median and ulnar nerves were smaller in AIDP patients than in Axonal GBS patients insert ignore into journalissuearticles values(p<0.001, p=0.004);. CNAPs of the right and left sural nerves were not different between the two groups insert ignore into journalissuearticles values(p=0.140, p=0.099);. SS-M / SS-U was observed in 1insert ignore into journalissuearticles values(10%);/1insert ignore into journalissuearticles values(10%); and 6insert ignore into journalissuearticles values(50%);/4insert ignore into journalissuearticles values(33%); of axonal GBS and AIDP patients, respectively insert ignore into journalissuearticles values(p=0.074 for SS-M, p =0.323 for SS-U);. There was a positive correlation between right median / ulnar nerve CNAP amplitudes and sural nerve CNAP amplitude insert ignore into journalissuearticles values(p=0.003 r=0.623 / p<0.001 r=0.850);. Conclusion: This study showed that the sural nerve conduction study findings may not be different in axonal GBS and AIDP patients. There may be a relationship between CNAPs of median/ulnar nerves and CNAPs of sural nerves.
Keywords : Acute inflammatory demyelinating polyradiculoneuropathy, Guillain Barré syndrome, Sensory nerve conduction study, Sural sparing