Assessing of antiradical and antioxidant activities of -carnitine, L-carnitine, Coenzyme Q10 and Beta Carotene dietary supplements

Authors : Yeşim Dağlıoğlu

Pages : 45-50

Doi:10.38001/ijlsb.1569828

View : 52 | Download : 70

Publication Date : 2025-04-15

Article Type : Research Paper

Abstract :In this study, common tests such as 2,2-diphenyl-l-picrylhydrazyl (DPPH) assay, hydrogen peroxide (H2O2) and superoxide anion (O·̄2 ) radical scavenging activity were exerted to measure the antioxidant activities of L-carnitine, Coenzyme Q10 (Co-Q10) and β-carotene dietary supplements. Antiradical and antioxidant capacities were evaluated comparatively with these tests. The highest free radical scavenging activity was observed in β-carotene (H2O2 73%; O·̄2 69%), while the lowest activity was recorded in L-carnitine (H2O2 59%; O·̄2 67%). The radical scavenging activity of these dietary supplements was discovered to be significantly different from each other (P < 0,05). The antiradical activities of these dietary supplements were measured colorimetrically based on their DPPH radical scavenging ability. The effective concentrations (EC50) values of β-carotene, Co-Q10, L-carnitine and methanol solutions were measured as 10.060, 28.990 and 146.682 μg/mL after 30 min, respectively. These results demonstrate the potent antioxidant and antiradical activities of all three dietary supplements compared to ascorbic acid. It can only be said that the antiradical activity of L-carnitine is lower than the others, suggesting that this may be due to kinetic behavior.
Keywords : Antioksidan, β-karoten, DPPH, Koenzim Q10, L-karnitin