Evaluation of phenolic profile, antioxidant and anticholinesterase effects of Fuscoporia torulosa

Authors : Mehmet Emin DURU, Gülsen TELÇAYAN, Ebru DEVECİ

Pages : 79-89

Doi:10.21448/ijsm.496327

View : 18 | Download : 9

Publication Date : 2019-03-16

Article Type : Research Paper

Abstract :In this study, we investigated antioxidant and anticholinesterase activities of the hexane, chloroform, acetone, methanol and water extracts of F. torulosa mushroom with total phenolic contents. Also, HPLC-DAD was used to identify phenolic profile of F. torulosa. The acetone and methanol extracts of F. torulosa with the highest total phenolic contents showed the highest antioxidant activity in all assays except metal chelating assay. Furthermore, antioxidant activities of the acetone and methanol extract were found to be higher than α-tocopherol and BHA used as standards in DPPH•, ABTS•+ and CUPRAC assays. When F. torulosa hexane extract insert ignore into journalissuearticles values(41.34±1.50 %); showed moderate AChE inhibitory activity, the acetone insert ignore into journalissuearticles values(40.78±0.30 %); and methanol insert ignore into journalissuearticles values(45.39±0.65 %); extracts of F. torulosa indicated moderate BChE inhibitory activity. Major phenolic compounds were identified as trans-2-hydroxy cinnamic acid insert ignore into journalissuearticles values(10.05 µg/g);, gallic acid insert ignore into journalissuearticles values(5.01 µg/g); and p-coumaric acid insert ignore into journalissuearticles values(3.04 µg/g);. These results suggest that F. torulosa mushroom could be used as a valuable natural antioxidant source for pharmaceutical industry.
Keywords : Fuscoporia torulosa, Phenolic profile, HPLC DAD, Antioxidant activity, Anticholinesterase activity