Promising antioxidant activity of crude extract from Calliandra tweedii Benth

Authors : Kátia DOS SANTOS, Alice NAGAİ, Carmen PALACİOS, Bruno EVANGELİSTA, Carlos PRİANTE, Débora ZAMBAN, Claudia FURLAN

Pages : 59-70

Doi:10.21448/ijsm.953427

View : 18 | Download : 9

Publication Date : 2023-03-26

Article Type : Research Paper

Abstract :The interest in medicinal plants encourages new research studies on plant extracts, as they are sources for treatments in medicine, agriculture, and veterinary. Calliandra tweedii is a native Brazilian species with broad use in folk medicine. This study aimed to examine the leaf crude extract insert ignore into journalissuearticles values(CE); of C. tweedii and its methanolic insert ignore into journalissuearticles values(MP); and hexane insert ignore into journalissuearticles values(HP); phases concerning total phenolic compounds insert ignore into journalissuearticles values(TPC);, proanthocyanidins insert ignore into journalissuearticles values(PRO);, and flavonoid profile, and correlate it to their antioxidant activity insert ignore into journalissuearticles values(DPPH and FRAP);. CE and MP revealed high contents of TPC, PRO and high antioxidant activity insert ignore into journalissuearticles values(DPPH and FRAP); in relation to HP. Contrarily, HP showed reduced antioxidant activity, according to the scarce phenolic constituents obtained from the partition. Five flavonols were detected by HPLC-UV-DAD, being quercitrin the major constituent. Also, one kaempferol derivate and a series of three quercetin derivates were detected. Strong positive correlations were observed between DPPH, FRAP, and phenolic compounds. These discoveries are important to highlight the promising antioxidant activity of CE of C. tweedii, which could contribute to the expansion of popular herbal medicines and new drug discovery.
Keywords : Medicinal plants, Flavonoid, HPLC UV DAD, Proanthocyanidin, Antioxidant activity