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  • İstanbul Journal of Pharmacy
  • Volume:48 Issue:2
  • Triterpenoids from Scorzonera veratrifolia Fenzl

Triterpenoids from Scorzonera veratrifolia Fenzl

Authors : Betül Çetin, Hasan Şahin, Aynur Sarı
Pages : 23-27
View : 32 | Download : 12
Publication Date : 2018-08-31
Article Type : Research Paper
Abstract :DOI: 10.5152/IstanbulJPharm.2018.410411 The genus Scorzonera insert ignore into journalissuearticles values(Asteraceae); has several species which are used as a vegetable and in folk medicine all around the world. A phytochemical study was carried out on petroleum ether fraction of methanol extract obtained from the roots of Scorzonera veratrifolia Fenzl insert ignore into journalissuearticles values(Bitlis / Turkey); to investigate the terpenoid composition of the plant. Column chromatography, preparative thin layer chromatography and gas chromatography insert ignore into journalissuearticles values(GC); were used for separation of the compounds. Their structures were determined by using GC-MS and NMR techniques. Seventeen triterpenoids insert ignore into journalissuearticles values(ß-amyrin, ß-amyrin acetate, ß-amyrinone, germanicol, germanicol acetate, germanicone, α-amyrin, α-amyrin acetate, α-amyrinone, ψ – taraxasterol, ψ – taraxasterol acetate, taraxasterol, taraxasterol acetate, lupeol, lupeol acetate, lupenone, fern-7-en-3-one); and one sterol insert ignore into journalissuearticles values(ß-sitosterol); were determined. The presence of these compounds has been shown for the first time in S. veratrifolia. α-amyrinone, ß-amyrin, ß-amyrinone, ψ – taraxasterol and ψ – taraxasterol acetate are new for the genus Scorzonera.
Keywords : Scorzonera veratrifolia, triterpenoids, sterol, GC MS

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