A new approach for the synthesis of N,N’-bis(phenoxyacetyl)hydrazines

Authors : Çağla Begüm APAYDIN, Zafer CESUR

Pages : 61-63

View : 54 | Download : 10

Publication Date : 2019-08-01

Article Type : Research Paper

Abstract :DOI : 10.26650/IstanbulJPharm.2019.19002 This report is about an unexpected formation of N,N’-bisinsert ignore into journalissuearticles values(substituted phenoxyacetyl); hydrazine derivatives. The reaction between N’-insert ignore into journalissuearticles values(4-ethylcyclohexylidene);phenoxyacetohydrazide with sulfanyl acids to obtain 4-thiazolidinones s,  gave an unexpected product, N,N’-bisinsert ignore into journalissuearticles values(phenoxyacetyl);hydrazine, with high purity instead of the expected cyclocondensation product.  When repeating the reaction with p-toluenesulfonic acid under the same conditions, the reaction resulted in the same compound. This indicates that two molecules of N’-insert ignore into journalissuearticles values(4-ethylcyclohexylidene);phenoxyacetohydrazide were involved in the reaction. The reaction can be applied as a different and new procedure for the synthesis of several N,N’-bisinsert ignore into journalissuearticles values(substituted phenoxyacetyl);hydrazine derivatives.  Cite this article as: Apaydın ÇB, Cesur Z insert ignore into journalissuearticles values(2019);. A new approach for the synthesis of N,N’-bisinsert ignore into journalissuearticles values(phenoxyacetyl);hydrazines. Istanbul J Pharm 49 insert ignore into journalissuearticles values(2);: 61-63.
Keywords : Diacylhydrazines, sulfanyl acid, reaction mechanism

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