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  • İstanbul Journal of Pharmacy
  • Volume:38
  • HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF CEFACLOR AND CEPHALEXIN USING FLUORESCENCE ...

HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF CEFACLOR AND CEPHALEXIN USING FLUORESCENCE DETECTION FOLLOWING PRECOLUMN DERIVATIZATION

Authors : S Özkirimli, Z Cesur, G Çapan S ÖZKIRIMLI, Z CESUR, G ÇAPAN
Pages : 87-93
View : 41 | Download : 11
Publication Date : 2013-06-25
Article Type : Research Paper
Abstract :Sefalosporin grubu antibiotiklerden sefaklor ve sefaleksininin yüksek performanslı sıvı kromatografisi ile miktar tayini yapılmış, fenilglisin internal Standard olarak kullanılmıştır. Yöntem oc-amino grubu taşıyan sefalosporinlerin dansil klorür ile reaksiyonuna dayanmaktadır. Önerilen yöntem farmasötik preparatlar için güvenilir ve doğru sonuçlar vermektedir.
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