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  • İstanbul Journal of Pharmacy
  • Volume:39
  • BRINE SHRIMP LETHALITY BIOASSAY OF GLAUCIUM GRANDIFLORUM VAR. GRANDIFLORUM

BRINE SHRIMP LETHALITY BIOASSAY OF GLAUCIUM GRANDIFLORUM VAR. GRANDIFLORUM

Authors : A Sari, Ç Ünsal, İ Sarioğlu A SARI, Ç ÜNSAL, İ SARIOĞLU
Pages : 57-60
View : 60 | Download : 16
Publication Date : 2013-06-25
Article Type : Research Paper
Abstract :Türkiye\`nin 3 farklı bölgesinden toplanan Glaucium grandiflorum Boiss. et Huet var. grandiflorum örneklerinin toprak üstü kısımlarından elde edilen alkaloit ekstreleri ve bu ekstrelerden elde edilen majör alkaloitler allokriptopin, protopİn, insert ignore into journalissuearticles values(+);-izokoridin, insert ignore into journalissuearticles values(+);-korİdin üzerinde brİne shrimp lethality testi yapılarak sitotoksisiteleri İncelenmiştir. Glaucium grandiflorum var. grandiflorum türünün 3 örneği de önemli oranda sitotoksik aktİvite göstermiştir. Allokriptopin, protopin, insert ignore into journalissuearticles values(+);-izokoridin, insert ignore into journalissuearticles values(+);-koridin sırasıyla 15.92, 37.51, 237.24, 75.95 LC50 değerleri ile kuvvetli sitotoksik aktivite göstemiştir.  
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