ANTIMUSCARINIC EFFECTS OF AMITRIPTYLINE HCI AND OPIPRAMOLE HCI IN RAT ILEUM AND RAT DUODENUM

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İstanbul Journal of Pharmacy
Volume:32
ANTIMUSCARINIC EFFECTS OF AMITRIPTYLINE HCI AND OPIPRAMOLE HCI IN RAT ILEUM AND RAT DUODENUM

ANTIMUSCARINIC EFFECTS OF AMITRIPTYLINE HCI AND OPIPRAMOLE HCI IN RAT ILEUM AND RAT DUODENUM

Authors : S Aydin O ÖZDEMİR

Pages : 43-50

View : 35 | Download : 12

Publication Date : 2015-09-09

Article Type : Research Paper

Abstract :Arnitriptyline, a tricyclic antidepressant which is mainly used for major depression treatment, was investigated about its antimuscarinic effects and as a result it was found generally non-selective and 100 fold less active than atropine insert ignore into journalissuearticles values(1,2,3,4);. There are no satisfactory information about opipramole\`s antirnuscarinic activity and selectivity. Experiments were based on measuring agonist and antagonist responses in isolated tissues in physiological conditions. Key words: Antimuscarinic activity, Tricyclic antidepressants, Arnitriptyline, Opipramole.
Keywords : Antimuscarinic activity, Tricyclic antidepressant, Arnitriptyline, Opipramole

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