Systemic Inflammatory Response Indices in the Clinical Management of Patients Monitored for Tubo-Ovarian Abscess

Authors : Ayşe Betül Tın, Sümeyye Yılmaz, Hilal Uslu Yuvacı
Pages : 190-198
Doi:10.34084/bshr.1779467
View : 45 | Download : 147
Publication Date : 2025-12-20
Article Type : Research Paper
Abstract :Aim: This study aimed to evaluate the potential usefulness of the systemic immune response index (SIRI) and systemic immune inflammation index (SII) as biomarkers for forecasting disease severity and clinical outcomes in patients receiving treatment for tubo-ovarian abscess (TOA). Materials and Methods: The records of 64 patients diagnosed and treated for TOA between January 2021 and December 2023 were retrospectively analyzed. The values of SIRI (neutrophil × monocyte / lymphocyte ratio) and SII (neutrophil × platelet / lymphocyte ratio) were calculated using pre- and post-treatment complete blood count parameters. Results: In this study, in patients receiving only medical treatment, a significant reduction was noted in hemoglobin, neutrophil, leukocyte, monocyte, CRP, SII, and SIRI values after treatment. In contrast, platelet values significantly increased (p<0.05). Among patients undergoing combined medical and surgical therapy, significant reductions were observed in hemoglobin, neutrophil, leukocyte, monocyte, CRP, SII, and SIRI values. At the same time, lymphocyte and platelet levels significantly increased after treatment compared to pre-treatment levels (p<0.05). When comparing pre- and post-treatment measurements in all patients, significant decreases were observed in hemoglobin, leukocyte, neutrophil, and monocyte levels, and significant increases in lymphocyte and platelet levels were detected (p<0.05). CRP, SII, and SIRI values significantly decreased after treatment (p<0.001). Conclusion: Systemic inflammatory indices are gaining importance in the clinical follow-up of TOA, A critical disease associated with marked morbidity and mortality. Comprehensive prospective studies are needed to validate their use as inflammatory markers in the management of TOA.
Keywords : Tubaovaryan apse, sistemik immün yanıt indeksi, sistemik immün inflamasyon indeksi

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