Canine transmissible veneral tumor:etiology, diagnosis and treatment

Authors : Çağla Nur KÜÇÜKBEKİR, Zeynep GÜNAY UÇMAK, Çağatay TEK

Pages : 57-65

Doi:10.30704/http-www-jivs-net.882280

View : 25 | Download : 7

Publication Date : 2021-04-30

Article Type : Review Paper

Abstract :Transmissible venereal tumor insert ignore into journalissuearticles values(TVT); is a round cell type neoplasia that is transmitted by mating and physical transfer of tumor cells. It is one of the most common benign tumors in dogs that can be seen in both gender. The external genital area is the main location of the tumor. However, internal organ metastasis has been reported. The most common clinical signs are lobular masses which are seen in the caudal part of the penis, in the posterior region of the vagina and at the vestibulovaginal junction. Nodular lesions with rapid bleeding are the most pronounced clinical finding. Initially, the small tumor forms into a large ulcerated mass in the next periods. Simultaneously, the volume of the tumor increases and the lesions are seen multilobular, cauliflower-like, brittle, hyperemic, and hemorrhagic. The most practical diagnostic method of the tumor is vaginal cytology. Cytology findings are characterized by the round or oval cells which have, pale blue or colorless cytoplasm with cytoplasmic vacuoles and a prominent nucleus. Chemotheraphy is the most effective treatment method. The weekly intravenous administration of vincristine suplhate given for 3 weeks on average reveals that the treatment success rate is beyond 90%. In this review, etiology, clinical findings, diagnosis and treatment of TVT are presented.
Keywords : Dog, Neoplasia, Vagina, Vincristine