Correlation between Phenolic Composition and Biological Properties of Propolis and Heavy Metal Contents

Authors : María İnmaculada GONZÁLEZMARTÍN, Eddy Valentín BETANCESSALCEDO, İsabel REVILLA, Ana María VIVARQUINTANA

Pages : 46-46

View : 11 | Download : 10

Publication Date : 2018-12-08

Article Type : Conference Paper

Abstract :The presence of heavy metals in propolis is associated with the environmental pollution of anthropic origin around the apiaries via various sources such as air, water, plants and soil. Although the presence of these compounds could affect the biological properties of the propolis, the correlation between them has not been previously studied. Then, the aim of this work was to stablish the correlations between the levels of some heavy metals such as lead, chromium, nickel, copper or zinc and phenolic composition and biological properties such as antioxidant or antibacterial activities. For this work, 44 propolis samples of different geographic locations were analyzed: Chile insert ignore into journalissuearticles values(Biobio region n=10); and Spain insert ignore into journalissuearticles values(Galicia n=12 and Castilla y León n=22);. The mineral composition analysis was performed using ICP-MS insert ignore into journalissuearticles values(Inductively Coupled Plasma Mass Spectrometry);. Antioxidant activity was measured using ABTS, DPPH and inhibiting activity of the linoleic acid/-caroten radical assays. Phenolic acids and their derivatives were determined by HPLC and biocide properties using the Five-Plate test. Pearson correlations were calculated with SPSS statistic package.              The results show a negative correlation between antibacterial activity similar to betalactamic antibiotics with nickel insert ignore into journalissuearticles values(p<0.01); and chromium insert ignore into journalissuearticles values(p<0.01); levels. The lead content was negatively correlated with phenolic acids and their derivatives. This correlation was statistically significant for the cynamil capheoil ester insert ignore into journalissuearticles values(p<0.05);. The zinc and copper contents were positively correlated with cumaric acid and cinnamic derivatives insert ignore into journalissuearticles values(p<0.05); respectively. Heavy metal levels were in general negatively correlated with antioxidant activity and these correlations were significant for copper insert ignore into journalissuearticles values(p<0.05); and lead insert ignore into journalissuearticles values(p<0.01);.
Keywords : Propolis, Heavy metal content, Phenolic Composition