Evaluation of Patient Follow-up with Transient Hypogammaglobulinemia in Infancy Diagnosis

Authors : Alaaddin YORULMAZ, Hasibe ARTAÇ, İsmail REİSLİ

Pages : 15-20

Doi:10.16899/gopctd.534014

View : 63 | Download : 19

Publication Date : 2019-03-27

Article Type : Research Paper

Abstract :Introduction: In this study, we aimed to investigate the clinical, laboratory and demographic characteristics of patients with THI who were admitted with the suspicion of recurrent infection and immunodeficiency. Methods: The study included 287 patients who were followed up with the diagnosis of transient hypogammaglobulinemia in infancy at Selçuk University Meram Faculty of Medicine, Child Health and Diseases Department and Department of Pediatric Allergy and Immunology, between November 2001 and November 2006. The age, gender, the age of the complaints and diagnosis, clinical features, family history and laboratory findings of the patients were examined. The data of the patients were collected by using the hospital file and the records in the Pediatric Immunology cards. Results: 195 insert ignore into journalissuearticles values(67.9%); of the patients were male and 92 insert ignore into journalissuearticles values(32.1%); were female insert ignore into journalissuearticles values(p <0.05);. The M/F ratio was 2.1. The age of diagnosis ranged from 8 months to 48 months with a mean of 24.6±11.3 months. The duration between the complaints and the age of diagnosis was between 1 and 63 months and the mean age was 13.5±8.6 months. Complaints of the patients were recurrent upper respiratory tract infection insert ignore into journalissuearticles values(URTI); 54.35% insert ignore into journalissuearticles values(n:156);, lower respiratory tract infection insert ignore into journalissuearticles values(LRTI); 50.52% insert ignore into journalissuearticles values(n:145);, sinusitis 41.26% insert ignore into journalissuearticles values(n:118);, recurrent otitis, 28.22% insert ignore into journalissuearticles values(n:81);, asthma finding 12.89% insert ignore into journalissuearticles values(n=37);, allergic skin and rhinitis findings 10.45% insert ignore into journalissuearticles values(n:30);, gastroenteritis 6.96% insert ignore into journalissuearticles values(n:20);, urinary tract infection 4.18% insert ignore into journalissuearticles values(n:12);, and moniliazis was 3.83% insert ignore into journalissuearticles values(n:11);. Conclusion: THI is usually a self-recovering disease around three years of age. In order to prevent complications such as chronic lung disease and to reduce morbidity, it is important to follow up the cases regularly.
Keywords : Transient hypogammaglobunemia, immunodeficiency

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