The Prognostic Value of Systemic Immune Inflammation Index in Children with Carbon Monoxide Poisoning

Authors : Emine ÖZDEMİR KAÇER

Pages : 879-884

Doi:10.16899/jcm.1347034

View : 63 | Download : 48

Publication Date : 2023-09-30

Article Type : Research Paper

Abstract :Backgrounds: Carbon monoxide insert ignore into journalissuearticles values(CO); is an odorless and colorless gas that forms when organic materials burn incompletely. Children are more susceptible to CO poisoning than adults because their respiratory and immune systems are still developing. The systemic immune inflammation index insert ignore into journalissuearticles values(SII); is a marker that reflects the balance between inflammation and immunity. Aims: In this study, we investigate the relationship between CO poisoning in children and SII. Materials and Methods: We conducted a retrospective observational study involving pediatric patients insert ignore into journalissuearticles values(age <18 years); diagnosed with CO poisoning and treated at XXX University Training and Research Hospital, a tertiary medical center, from January 2018 to January 2023. We included consecutive pediatric patients insert ignore into journalissuearticles values(age <18 years); with CO poisoning who had available clinical and laboratory data and were treated at our hospital. Results: The study included 393 patients with a mean age of 7.24 insert ignore into journalissuearticles values(± 4.67); years, of whom 184 insert ignore into journalissuearticles values(46.8%); were male. When comparing COHb groups, significant statistical differences emerged between the groups regarding GCS, pH levels, occurrences of dizziness, confusion, seizures, lethargy, and prognosis insert ignore into journalissuearticles values(p<0.05);. When comparing lactate groups, significant differences were observed between the groups concerning GCS, COHb levels, pH levels, occurrences of confusion, lethargy, prognosis, and LOS insert ignore into journalissuearticles values(p<0.05);. Upon evaluating the SII, no statistically significant difference was found between the groups in terms of gender, COHb levels, lactate levels, LOS, and prognosis. Conclusion: SII cannot be considered a reliable predictor of the severity of carbon monoxide poisoning in children. Despite the evident inflammatory response triggered by exposure to carbon monoxide, the SII did not consistently correlate with the varying degrees of poisoning severity.
Keywords : Karbon monoksit zehirlenmesi, İnflamatuvar yanıt, Pediatrik hastalar, Şiddet değerlendirmesi, Sistemik immün inflamasyon indeksi SII,

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