USE OF HIGH-DOSE OF UROKINASE DURING CARDIOPULMONARY RESUSCITATION FOR CLINICALLY SUSPECTED MASSIVE PULMONARY EMBOLISM.

Authors : Luis CHİSCANO CAMON, Juan Carlos RUİZ RODRİGUEZ, Laura Dono ANSELMO, Adolf Ruiz SANMARTİN

Pages : 17-20

Doi:10.33706/jemcr.550556

View : 23 | Download : 9

Publication Date : 2019-01-01

Article Type : Other Papers

Abstract :Introduction: We are presenting 6 patients who suffered a cardiac arrest insert ignore into journalissuearticles values(CA); for suspected pulmonary embolism. Before establishing a definitive diagnosis, advanced life support insert ignore into journalissuearticles values(ALS); algorithm was initiated. Urokinase dosed as 15.000 UI/kg insert ignore into journalissuearticles values(weight); was administered initially, followed by 4.400 UI/Kg for 12 hours as a continuous intravenous perfusion. Two patients presented absolute contraindications for fibrinolytic therapy, however only one patient presented a major hemorrhagic complication. Global mortality rate was 83%. Case report: We present 6 cases of patients with CA due to MPE who were treated with high doses of urokinase during cardiopulmonary resuscitation and later admitted to the Intensive Care Unit insert ignore into journalissuearticles values(ICU);. Conclusion: Our observations suggest that the clinical suspected MPE with CA can also be one of the recommended applications of thrombolysis with high-dose bolus injection of thrombolytic with efficacy.
Keywords : cardiac arrest, cardiopulmonary resuscitation, pulmonary embolism, reperfusion