The impact and relationship of inflammatory markers and radiologic involvement in the COVID-19 patients

Authors : Merve Sefa SAYAR, Dilek BULUT, Sebahattin ÇELİK, Veysel BURULDAY, Remzi SARIKAYA, Nurettin KURT

Pages : 416-421

Doi:10.32322/jhsm.904196

View : 25 | Download : 11

Publication Date : 2021-07-15

Article Type : Research Paper

Abstract :Aim: In the study, it was aimed to investigate the relationship between inflammatory markers and radiology in COVID-19 patients. Material and Method: The study was conducted in the quarantine wards of a tertiary hospital between March and June 2020. Patients with a definite diagnosis of COVID-19 were included in the study. The lung damage of the patients caused by COVID-19 was determined by computed tomography and the relationship between lung damage and inflammatory markers was examined. Results: The mean age of 259 COVID-19 patients included in the study was 61.96 ± 14.076. Except for thrombocytopenia, all variables such as ferritin, D-dimer, thoracic computerized tomography insert ignore into journalissuearticles values(CT); involvement rates were significantly poorer in the patients requiring the care in ICU than the patients in wards insert ignore into journalissuearticles values(p<0.001);. No chronic disease was found in 193 insert ignore into journalissuearticles values(74.5%); of 259 patients. In multi-variate analyzes, elderly and high thoracic CT involvement rate were determined as independent variables determining the serious disease risks and are important parameters in assessing the need for ICU insert ignore into journalissuearticles values(p<0.05);. Ferritin value, D-Dimer value on the third day of admission, Neutrophil lymphocyte ratio and leukocyte count were found to be correlated with thoracic CT involvement rate insert ignore into journalissuearticles values(p <0.05);. Conclusion: It was observed that there were serious changes in the infection parameters of COVID-19 cases with advanced radiological involvement in the lung.
Keywords : COVID 19, intensive care unit, prognosis, SARS CoV 2