Prognostic value of blood gas lactate levels among COVID-19 patients who visited to emergency department

Authors : Erdem KURT, Suphi BAHADIRLI

Pages : 493-497

Doi:10.32322/jhsm.934484

View : 20 | Download : 12

Publication Date : 2021-07-15

Article Type : Research Paper

Abstract :Objective: Our aim in this study, to determine the relationship between the mortality status and the ICU requirement of COVID-19 patients, with their blood gas lactate levels at the time of admission to the ED. Material and method: This study was planned as retrospectively, all COVID-19 patients over the age of 18 who were admitted to the ED, had oropharyngeal /nasopharyngeal swabs and hospitalized between April 1, 2020 and June 31, 2020 were included. The primary outcome was in-hospital mortality. The secondary outcome is to determine the relationship between lactate levels and the ICU requirement Results: The study was completed with 265 patients after the inclusion and exclusion criteria were applied. The median insert ignore into journalissuearticles values(IQR); age of the patients was 43.0 insert ignore into journalissuearticles values(31.0 – 59.0);, and 132 insert ignore into journalissuearticles values(49.8%); were female. The comorbid diseases are; hypertension insert ignore into journalissuearticles values(HT);, cardiovascular disease and diabetes mellitus insert ignore into journalissuearticles values(DM); were in the first three places with 23.0%, 17.0%, 9.1%, respectively. The cut-off value of lactate to determined for ICU admissions was 2.92, and 4.25 for mortality.The AUC for ICU requirement was 0.718 ± 0.038 insert ignore into journalissuearticles values(95% CI, 0.644 - 0.792);, and AUC for mortality was 0.752 ± 0.058 insert ignore into journalissuearticles values(95% CI, 0.637 - 0.867);, insert ignore into journalissuearticles values(p <0.001 for both);. Conclusions: The COVID-19 pandemic has caused a serious mortality and morbidity problem worldwide. Our study found that hyperlactatemic COVID-19 patients had higher ICU requirement and mortality rates.
Keywords : covid 19, lactate, prognostic, mortality