Sonographic evaluation of intra-abdominal organs in children with familial Mediterranean fever

Authors : Ergün SÖNMEZGÖZ, Fitnet SÖNMEZGÖZ

Pages : 662-665

Doi:10.32322/jhsm.948957

View : 31 | Download : 17

Publication Date : 2021-09-05

Article Type : Research Paper

Abstract :Objective: The reticuloendothelial system is rarely assessed in patients with familial Mediterranean fever insert ignore into journalissuearticles values(FMF);. We aimed to evaluate the size of the liver and spleen by ultrasonography in children and adolescents with FMF and compare it to their healthy peers. Material and Method: Patient data were evaluated by height, weight, and age and compared with those of healthy controls. Results: A total of 86 children with FMF diagnosed using the Turkish Pediatric Criteria and 54 healthy children were included. The extent of splenomegaly was 27.9% in the FMF group. The mean spleen length was 99.84±17.4 mm in patients and 93.44+15.49 mm in controls insert ignore into journalissuearticles values(p=0.03);. The mean liver length was 122.61±17.4 mm in patients and 117.71±16.04 mm in controls insert ignore into journalissuearticles values(p=0.104);. FMF appears to affect spleen length independently of anthropometric data insert ignore into journalissuearticles values(t=2.182; p=0.031);. Splenomegaly was accompanied by the M694V insert ignore into journalissuearticles values(32.55%, n=17); and E148Q insert ignore into journalissuearticles values(3.4%, n=3); mutations. Conclusion: FMF affects spleen length independently of anthropometric data. Splenomegaly may reflect subclinical inflammatory activity in FMF patients in remission. Spleen size can serve as a marker of subclinical inflammation during remission.
Keywords : Familial Mediterranean fever, ultrasonography, splenomegaly, children, inflammatory markers