Antibiotic resistance of Enterococcus species: 3-year data

Authors : Ali Korhan SİG, Tuğba KULA ATİK, Alev ÇETİN DURAN

Pages : 670-674

Doi:10.32322/jhsm.949498

View : 30 | Download : 12

Publication Date : 2021-09-05

Article Type : Research Paper

Abstract :Aim: The aim of this study is to investigate the prevalence of Enterococcus species and to evaluate susceptibilities to antimicrobial agents in a state insert ignore into journalissuearticles values(secondary); hospital. Material and Methods: A total of 1676 enterococci strains insert ignore into journalissuearticles values(490 E.faecium, 1146 E.faecalis, 10 E.casseliflavus/E.gallinarum and 30 other Enterococcus species); isolated from cultures obtained from January 2017 to December 2019 in XXX Hospital were included. Blood cultures were incubated in automated device insert ignore into journalissuearticles values(Render Biotech Co.Ltd., PRC);. Other cultures were incubated with conventional methods. Grown colonies were identified by PhoenixTM 100 automated system insert ignore into journalissuearticles values(Becton Dickinson, USA);. Identifications that need confirmation or strains identified to genus level were further evaluated with conventional techniques. Antimicrobial susceptibility testing were performed by same system, Kirby-Bauer disc diffusion and gradient strip method according to EUCAST guidelines. Results: 43.1%, 27.1%, 14.7% and 15.1% of enterococci were isolated from urine, blood/sterile body fluids, wound/abscess and other samples. Majority of the strains were ciprofloxacin insert ignore into journalissuearticles values(72.0%); and levofloxacin insert ignore into journalissuearticles values(74.1%); resistant, and more than 40% showed ampicillin and high-level gentamicin resistance. Glycopeptide resistance was relatively high insert ignore into journalissuearticles values(5.4%);, especially when considering E.faecium insert ignore into journalissuearticles values(12.1%);. There was not any tigecycline and linezolid resistance. Conclusions: Antimicrobial resistance is a serious and growing public health problem affecting all countries, which is not just a topic of medicine, but multiple sectors such as commercial companies, food industry, veterinarians, etc. High percentages of resistance strongly indicate to get a local action, which should be followed by national and global one.
Keywords : enterococci, vancomycin, antimicrobial stewardship, EUCAST, CLSI