Complications with moderate-to-severe COVID-19 during hospital admissions in patients with pneumonia

Authors : Tuğçe ŞAHİN ÖZDEMİREL, Esma Sevil AKKURT, Özlem ERTAN, Mehmet Enes GÖKLER, Berna AKINCI ÖZYÜREK

Pages : 766-771

Doi:10.32322/jhsm.946871

View : 31 | Download : 14

Publication Date : 2021-09-24

Article Type : Research Paper

Abstract :Introduction: Coronavirus disease 2019 insert ignore into journalissuearticles values(COVID-19);, caused by SARS-CoV-2 insert ignore into journalissuearticles values(severe acute respiratory syndrome coronavirus 2); is an infectious disease that has caused significant mortality and morbidity worldwide. COVID-19 is known to cause complications, such as myocardial damage, acute coronary syndrome, deep vein thrombosis, pulmonary embolism, arrhythmia, heart failure, acute ischemic stroke, liver damage, cytokine storms, ischemia-reperfusion damage and side effects of drug treatments. In our study, we aimed to evaluate the complications that developed during hospitalizations in patients with moderate-to-severe COVID-19 related pneumonia who were hospitalized in our COVID-19 service. Material and Method: This study included patients with moderate-to-severe COVID-19 pneumonia with a positive reverse transcriptase polymerase chain reaction insert ignore into journalissuearticles values(RT-PCR); test who were treated in our COVID-19 service between November 2020 and January 2021. Their demographic characteristics, treatment regimens, baseline laboratory values and complications during their hospitalization were retrospectively recorded. Results: The study group had a mean age of 62.92± 14.60 years and 40.6% insert ignore into journalissuearticles values(n= 55); were female. Approximately 35.3% insert ignore into journalissuearticles values(n= 48); of the patients developed complications due to COVID-19 during their follow-up period. Of the patients with complications, 63.8% insert ignore into journalissuearticles values(n: 30); were male, most common complications were elevated liver enzymes insert ignore into journalissuearticles values(47.9%); and pulmonary thromboembolism insert ignore into journalissuearticles values(20.8%);. Of those patients with complications, the most common comorbidities were hypertension insert ignore into journalissuearticles values(40.4% [n= 19]);, diabetes mellitus insert ignore into journalissuearticles values(25.5% [n=12]); and cardiovascular disease insert ignore into journalissuearticles values(23.4% [n=11]);. There were no significant relationships between the presence of complications and age, sex or comorbid diseases insert ignore into journalissuearticles values(p>0.05 for each);. Conclusion: There are more underlying conditions, such as hypertension, diabetes mellitus, cardiovascular disease, chronic lung disease in hospitalized patients with moderate-to-severe pneumonia compared to outpatients with COVID-19 pneumonia. Complications develop, especially in the management of COVID-19 pneumonia, which affect the treatment process and patient mobilization.
Keywords : complication, COVID 19, pneumonia