The efficiency of HALP score, neutrophil-lymphocyte ratio, and platelet-lymphocyte ratio in predicting mortality in intensive care patients

Authors : Salih KOCAOĞLU, Tufan ALATLI

Pages : 201-206

Doi:10.32322/jhsm.1017889

View : 23 | Download : 10

Publication Date : 2022-01-17

Article Type : Research Paper

Abstract :Objective: The HALP Score, which is a combination of hemoglobin, albumin, lymphocytes, and platelets, is a new index that shows nutritional status and systemic inflammation, provides information about patient prognosis. In this study, we aimed to investigate the relationship of HALP score, platelet-lymphocyte ratio insert ignore into journalissuearticles values(PLR);, neutrophil-lymphocyte ratio insert ignore into journalissuearticles values(NLR); and with poor prognosis in intensive care patients. Material and Method: Our study was designed retrospectively on patients admitted from the emergency department insert ignore into journalissuearticles values(ED); to the intensive care unit insert ignore into journalissuearticles values(ICU);. HALP scores, PLR and NLR values were calculated from the hemoglobin, albumin, lymphocyte, platelet and neutrophil values taken from the patients within 24 hours. One-week and three-month mortality were determined as poor outcomes. The relationship between results and poor outcomes was investigated. Results: A total of 250 patients were included in the study. The median age of the patients was 72.5%, and 43.6% insert ignore into journalissuearticles values(n=109); were female. When the variables between survivors and non-survivors were compared, NLR was found to be significantly higher in non-survivors. In addition, there was a significant difference between the two groups in terms of both one-week and three-month mortality regarding age, albumin, lymphocyte, and thrombocyte values. When we analyzed the diagnostic performances of HALP Score, NLR, and PLR for one-week and three-month mortality, only NLR showed significant diagnostic performance. The optimal cut-off point for NLR for both one-week and three-month mortality was 8.22 insert ignore into journalissuearticles values(for one-week mortality: AUC=0.598, p=0.007; for three-month mortality: AUC=0.592, p=0.011);. Conclusion: It was observed that the HALP score was not an effective parameter in predicting prognosis in intensive care patients. It is thought that NLR has a significant relationship with one-week and three-month mortality and can be used as an effective parameter in the prediction of prognosis in intensive care patients.
Keywords : Intensive care, halp score, neutrophil lymphocyte ratio, platelet lymphocyte ratio