The relationship of obstructive sleep apnea risk with the disease severity and clinical parameters in COPD population

Authors : Ali Onur KELEŞ, Sezgi ŞAHİN DUYAR, Funda AKSU, Selma FIRAT

Pages : 67-72

Doi:10.32322/jhsm.992192

View : 24 | Download : 12

Publication Date : 2022-01-17

Article Type : Research Paper

Abstract :Aim: Obstructive sleep apnea syndrome insert ignore into journalissuearticles values(OSAS); and chronic obstructive pulmonary disease insert ignore into journalissuearticles values(COPD); have common pathophysiological mechanisms affecting the prognosis of each other. This study aims to investigate the relationship between the presence of OSA risk and the severity of COPD and to determine the possible clinical features for OSA risk for COPD patients. Material and Method: The patients insert ignore into journalissuearticles values(n=181); who applied to the outpatient clinics of pulmonology between September - November 2019 with the diagnosis of COPD, were analyzed cross-sectionally. Demographic features, anthropometric measurements, comorbidities, smoking status, and severity of dyspnea, respiratory functions, and exacerbation frequency in the last year were evaluated. All patients were questioned with the Epworth sleepiness scale insert ignore into journalissuearticles values(ESS); for detecting excessive daytime sleepiness insert ignore into journalissuearticles values(EDS);, and the STOP-Bang for determining the risk of OSA. Results: The rate of diabetes, waist and hip circumference measurements, median ESS score, and EDS ratio were found to be higher in patients with moderate/high OSA risk when compared to patients with low OSA risk. In the multivariate regression model; lower oxygen saturation insert ignore into journalissuearticles values(OR: 0.83; p=0.007); and higher ESS score insert ignore into journalissuearticles values(OR=1.28; p<0.001); were determined as independent risk factors affecting the OSA risk to be moderate/high. Conclusion: Low oxygen saturation, accompanying diabetes, high ESS score and, high waist-hip circumference stand out as useful factors in determining OSA risk in the COPD population. However, OSA risk was found to be the same among all COPD stages. We suggest that all COPD patients should be questioned for OSA risk regardless of the stage.
Keywords : Obstructive sleep apnea syndrome OSAS, Chronic Obstructive Pulmonary Disease COPD, Epworth sleepiness scale ESS