Correlation of vitamin D level with the clinical-radiological severity of COVID-19 in geriatric patients

Authors : Hüsnü BAYKAL, Ayşe Füsun ÜLGER

Pages : 771-777

Doi:10.32322/jhsm.1063405

View : 25 | Download : 11

Publication Date : 2022-05-30

Article Type : Research Paper

Abstract :Objective: This study was planned to investigate the effect of 25-OH-Vitamin D insert ignore into journalissuearticles values(Vit D); deficiency on clinical and radiological findings of coronavirus disease-2019 insert ignore into journalissuearticles values(COVID-19); in geriatric patients hospitalized due to COVID-19. Material and Method: Seventy-five patients who were treated for COVID-19 were reviewed retrospectively, and grouped in relation with their ages [insert ignore into journalissuearticles values(1); 65-74, insert ignore into journalissuearticles values(2); 75-84, insert ignore into journalissuearticles values(3); >84 years] and the severity of Vit D deficiency [insert ignore into journalissuearticles values(1); severe deficiency: 30 ng/mL]. The complaints on admission, comorbidities, intensive care unit insert ignore into journalissuearticles values(ICU); need, length of hospital stay, laboratory data, and mortality of the ones who had and did not have Vit D replacement insert ignore into journalissuearticles values(n=18/75); were recorded. The patients were analyzed for COVID-19 severity using radiological and clinical markers. Results: Moderate Vit D deficiency insert ignore into journalissuearticles values(10-20 ng/mL); was frequently detected. When the disease severity and Vit D levels were analyzed, it was found that the disease was more severe insert ignore into journalissuearticles values(46.6%); in the Vit D 30 ng/ml group, but there was no statistically significant difference among the groups. Low or high Vit D levels did not show any significant correlations with the severity of pneumonia or the thorax CT findings. The intensive care unit insert ignore into journalissuearticles values(ICU); admission rate was significantly lower in those who had Vit D replacement insert ignore into journalissuearticles values(p<0.001);. Conclusion: The ICU admission rate was lower in patients who had Vit D replacement, however, serum Vit D concentrations were not correlated with COVID-19 severity or mortality risk.
Keywords : COVID 19, vitamin D, pneumonia, elderly, intensive care unit