Predictors of colonic diverticulosis in non-elderly patients

Authors : Abdurrahman ŞAHİN, Mustafa CENGİZ, Oktay SARI

Pages : 740-745

Doi:10.32322/jhsm.1076167

View : 29 | Download : 12

Publication Date : 2022-05-30

Article Type : Research Paper

Abstract :Aim: To investigate the clinical and laboratory features patients under aged 65 years with diverticulosis and to compare them to subjects with no diverticula. Material and Method: This retrospective case-control study included subjects aged under 65 years who underwent a colonoscopy in the period from January 2016 to June 2018 for diverse indications. Patients with diverticulosis as detected by a colonoscopy were compared to patients without diverticulosis. The comparison parameters included demographic data, comorbidities, and laboratory parameters, including a complete blood count, blood biochemistry, erythrocyte sedimentation rate insert ignore into journalissuearticles values(ESR);, and C-reactive protein. Results: The study included 129 patients with diverticulosis and age and sex-matched 130 patients with no diverticula. Diverticula were predominantly left-sided in 64.3%, right-sided in 9.3%, and bilateral in 26.4%. Hypertension was more prevalent among patients with diverticulosis compared to control subjects insert ignore into journalissuearticles values(31% vs 17%, p<0.01);. The median ESR was higher in diverticulosis group than in control group insert ignore into journalissuearticles values(13±1.6 mm/h vs 9±0.9 mm/h, p=0.01);. The mean creatinine was higher insert ignore into journalissuearticles values(0.86±0.25mg/dL vs 0.76±0.19 mg/dL, p<0.01); and the mean albumin was lower insert ignore into journalissuearticles values(4.3±0.4 g/dL vs 4.5±0.3 g/dL, p<0.01); in diverticulosis group compared to control group. Hypertension, ESR, creatinine and albumin were independent predictors of the presence of diverticulosis in univariate and multivariate logistic regression analysis. Conclusion: It is important to determine the characteristic features of asymptomatic patients with diverticulosis in earlier ages. The presence of hypertension, in conjunction with high creatinine and low albumin values increase the probability of the presence of asymptomatic colonic diverticula.
Keywords : Albumin, colonic diverticula, creatinine, hypertension, non elderly