The protective role of low-dose acetylsalicylic acid use and relation with inflammatory and thrombotic parameters on radial artery occlusion in patients undergoing elective transradial coronary angiography

Authors : Nail Burak ÖZBEYAZ, Sadık AÇIKEL, Engin ALGUL, Haluk Furkan ŞAHAN, Faruk AYDINYILMAZ, Mehmet Ali FELEKOĞLU, Gökhan GÖKALP, İlkin GULIYEV

Pages : 1103-1109

Doi:10.32322/jhsm.1110150

View : 29 | Download : 11

Publication Date : 2022-07-20

Article Type : Research Paper

Abstract :Aim: Transradial angiography insert ignore into journalissuearticles values(TRA); is recommended in clinical practice; it is better than the transfemoral route to prevent site-related complications. Radial artery occlusion is one of the most seen significant complications after TRA. In the present study, the protective effect of low dose acetylsalicylic acid insert ignore into journalissuearticles values(ASA); use against the radial artery occlusion insert ignore into journalissuearticles values(RAO); and the predictive ability of some thrombotic and inflammatory factors for the development of RAO were investigated. Material and Method: One thousand two hundred fifty-four patients who planned for elective coronary angiography were screened to include transradial coronary angiography. The patients have grouped group I, who took ASA insert ignore into journalissuearticles values(100 mg); insert ignore into journalissuearticles values(n= 56);, and group II insert ignore into journalissuearticles values(n= 51);, who did not. Blood samples were taken immediately after sheath insertion and after the six hours of the sheath removal. The D-dimer and C-reactive protein values were analyzed between groups. In the first 24 hours after the procedure, the radial Doppler ultrasonography assessment was performed to detect RAO. Multivariable regression analysis was used to evaluate the independent risk factors for the TRA. Results: Eligible one hundred seven stable patients were included in the study. The demographic, laboratory and procedural characteristics were similar between the two groups insert ignore into journalissuearticles values(Table 2);. TRA was statistically lower in Group I compared to Group II. insert ignore into journalissuearticles values(n=3 vs. n=22, p=.001);. Multivariable regression analysis demonstrated that postprocedural higher D-dimer levels and non-ASA status were found to be the independent risk factors for RAO insert ignore into journalissuearticles values(OR insert ignore into journalissuearticles values(95% CI=1.235insert ignore into journalissuearticles values(1.014-1.582); p=.001, 5.534 insert ignore into journalissuearticles values(3.376-9.252);, p .05);. Conclusion: Preprocedural ASA use may have a protective role against the RAO. Pre- and post-procedural D-dimer levels can predict the thrombotic process in the early phase of the RAO.
Keywords : Acetylsalicylic acid, radial artery occlusion, D dimer, C reactive protein, protection