The relationship between polycystic ovary syndrome and irritable bowel syndrome

Authors : Naziye GÜRKAN, Mehmet AĞAR, Tuğba GÜRBÜZ

Pages : 1220-1224

Doi:10.32322/jhsm.1122473

View : 26 | Download : 11

Publication Date : 2022-09-25

Article Type : Research Paper

Abstract :Introduction: Polycystic ovary syndrome insert ignore into journalissuearticles values(PCOS); causes endocrine disorders that affect the functioning of the reproductive system and the body`s metabolic system. Bowel movement disorders and abdominal pain are common complaints of PCOS patients. Few studies have been performed on the relationship between PCOS and irritable bowel syndrome insert ignore into journalissuearticles values(IBS);, and the association between the two syndromes is unclear. Material and Method: In the study, 72 patients were enrolled at gynecology and obstetric clinic in Turkey. The control group were insert ignore into journalissuearticles values(n=34); and women with PCOS insert ignore into journalissuearticles values(n=38);. IBS diagnosis was made by using Roma IV criteria. Results: The results showed that IBS prevalence was similar in PCOS insert ignore into journalissuearticles values(52%); and the control group insert ignore into journalissuearticles values(50%); insert ignore into journalissuearticles values(p>0.05);. No statistically significant association was found between IBS-PCOS and non-IBS-PCOS in terms of gastrointestinal symptoms insert ignore into journalissuearticles values(p=0.685);. These symptoms were associated with PCOS rather than IBS. Significant differences have been observed between IBS-PCOS and non-IBS-PCOS for fasting insulin insert ignore into journalissuearticles values(FI);, luteinizing hormone insert ignore into journalissuearticles values(LH); and Homeostasis model assessment for insulin resistance insert ignore into journalissuearticles values(HOMA-IR); insert ignore into journalissuearticles values(p<0.05);. Significant differences have been observed between IBS-control and non-IBS-control for FI, fasting glucose and HOMA-IR insert ignore into journalissuearticles values(p<0.05);. Aging was significantly associated with co-occurrence with IBS and PCOS. Conclusion: Although many PCOS patients were diagnosed with IBS based on Rome IV criteria, no significant relationship was found between PCOS and IBS prevalence in the study subjects. The prevalence of gastrointestinal symptoms is similar in both groups insert ignore into journalissuearticles values(IBS-PCOS and PCOS only);. Age was an important risk factor for the co-occurrence of IBS and PCOS.
Keywords : Polycystic ovary syndrome, Irritable bowel syndrome, gastrointestinal symptoms