Association of COVID-19 vaccine with lymph node reactivity: an ultrasound-based study

Authors : Belma ÇEVİK

Pages : 1390-1393

Doi:10.32322/jhsm.1123597

View : 24 | Download : 15

Publication Date : 2022-09-25

Article Type : Research Paper

Abstract :Aim: Millions of people worldwide have been infected and died due to the pandemic caused by COVID-19. Vaccination is the most effective way to deal with the pandemic. Though vaccines are safe, they are not completely risk-free, and some side effects can occur after vaccination such as lymphadenopathy. This study, it was aimed to measure the lymph node reactivity that may develop after mRNA vaccination. Material and Method: A total of 50 healthy people were included in the study. Left axillary and supraclavicular ultrasound examinations were performed before and one week after the administration of the mRNA vaccine. Each patient was assessed for supraclavicular and level 1 axillary lymph region in terms of the presence, size insert ignore into journalissuearticles values(long and short axis);, and cortex thickness of the lymph nodes. Results: Of the patients participating in the study, 23 insert ignore into journalissuearticles values(46 %); were male, 27 insert ignore into journalissuearticles values(54 %); were female, and the median age was 33. In comparison, the difference in long, short axis and cortex diameter measurements of the supraclavicular lymph node before and after vaccination was found to be statistically significant insert ignore into journalissuearticles values(p=0.034, 0.021, 0.004, respectively);. Similarly, the difference in the long, short axis, and cortex thickness of the left axillary lymph node before and after vaccination was statistically significant insert ignore into journalissuearticles values(p<0.001, <0.001, <0.001, respectively);. Conclusion: Anti-Covid-19 vaccines may cause lymphadenopathy as a result of reactivation in lymph nodes in the left axillary and supraclavicular regions. When lymphadenopathy is detected in these regions, the vaccine should be questioned in the clinical history and ultrasound follow-up should be performed on the patient.
Keywords : Lymphadenopathy, COVID 19 vaccines, ultrasound