Malignant bone tumors around the knee: A single-center experience

Authors : Selami KARADENİZ, Furkan ERDOĞAN, Alparslan YURTBAY, İsmail BÜYÜKCERAN, Cahit Şemsi ŞAY, Nevzat DABAK

Pages : 1345-1350

Doi:10.32322/jhsm.1132982

View : 23 | Download : 18

Publication Date : 2022-09-25

Article Type : Research Paper

Abstract :Aim: This study aimed to determine the frequency of malignant bone tumors insert ignore into journalissuearticles values(primary and metastatic); seen around the knee in our region, the patients’ type and demographic characteristics, and the treatments’ outcomes. Material and Method: A retrospective analysis of the patients who were diagnosed and treated with histopathologically malignant tumors in the knee region in our hospital between 2004-2021 was performed from the hospital database. Patients’ complaints, demographic information, and diagnostic and imaging findings were examined. In addition, tumor types, tumor localization, and treatments applied were analyzed. Results: Malignant bone tumor was detected in 88 insert ignore into journalissuearticles values(35.7%); of 246 patients included in the study. The patients were 48 women and 40 men, with a mean age of 39.72±21.8 insert ignore into journalissuearticles values(6-76 years);. A total of 88 patients were divided into the pediatric group insert ignore into journalissuearticles values(<18 years; n=39); and the adult group insert ignore into journalissuearticles values(≥18 years; n=49);. The most common tumors were osteosarcoma in 54 insert ignore into journalissuearticles values(61.3%); and metastatic tumors in 22 insert ignore into journalissuearticles values(25%); patients. The most common localization of tumors was the distal femur with a rate of 75%. Metastasis was detected in 12 insert ignore into journalissuearticles values(18.2%); of 66 patients treated and followed up for primary malignant bone tumors. Limb sparing surgery was performed in 70 insert ignore into journalissuearticles values(79.5%);, and various levels of amputation were performed in 14 insert ignore into journalissuearticles values(15.9%);. Palliative radiotherapy was applied to two patients with metastatic lesions, while two patients who were in the neoadjuvant chemotherapy period died. The 5-year overall survival was 63.7%. Pediatric and adult age groups did not differ significantly in terms of survival insert ignore into journalissuearticles values(p=0.74);, gender insert ignore into journalissuearticles values(p=0.585);, and metastasis development insert ignore into journalissuearticles values(p=0.53);. Conclusion: The knee is a region that requires attention regarding bone tumors around it. As malignant bone tumors are rarely seen around the knee, a misdiagnosis may be made, and appropriate treatment may be delayed. Although the first diagnosis to come to mind for patients presenting with knee pain is trauma and growing pains, it must not be forgotten that a tumor could be the cause.
Keywords : Bone tumors, malign, knee, surgery