The relationship of nailfold capillaroscopy patterns with clinical features, functional status, pain and fatigue in patients with systemic sclerosis

Authors : Didem ERDEM GÜRSOY, Halise Hande GEZER, Sevtap ACER, Hatice Şule BAKLACIOĞLU, Mehmet Tuncay DURUÖZ  

Pages : 1468-1472

Doi:10.32322/jhsm.1133573

View : 24 | Download : 14

Publication Date : 2022-09-25

Article Type : Research Paper

Abstract :Aim: To identify the frequency of scleroderma-type capillaroscopic patterns and evaluate the association of capillaroscopic patterns with clinical parameters, functional status, fatigue, and pain in systemic sclerosis insert ignore into journalissuearticles values(SSc);. Material and Method: This cross-sectional study included SSc patients consecutively between January 2017 and January 2019. Cutaneous involvement was evaluated with the modified Rodnan skin score insert ignore into journalissuearticles values(mRSS);. The presence of digital ulcers, Raynaud phenomenon, interstitial lung disease, pulmonary hypertension, cardiac, gastrointestinal system insert ignore into journalissuearticles values(GIS);, renal, joint and muscle involvement were recorded. The severity of the Raynaud phenomenon, fatigue, pain, and patient global assessment insert ignore into journalissuearticles values(PGA); was assessed on the Visual Analogue Scale insert ignore into journalissuearticles values(VAS);. The Health Assessment Questionnaire insert ignore into journalissuearticles values(HAQ); and the Duruoz Hand Index insert ignore into journalissuearticles values(DHI); were used to assess physical disability and hand function, respectively. Nailfold videocapillaroscopic examinations of the patients were performed, and they were classified into four groups, including normal/non-specific, early, active, and late scleroderma patterns. Results: The mean age of 32 patients with SSc insert ignore into journalissuearticles values(31 female, one male); was 48.93±12.77. Anormal capillaroscopic examination findings were detected in 93.7% of the patients, and the most common capillaroscopic pattern was the active pattern. The comparison of scleroderma pattern groups revealed no difference in age insert ignore into journalissuearticles values(p=0.224);, but disease duration was shorter in the early pattern group insert ignore into journalissuearticles values(p=0.005);. The duration and severity of the Raynaud phenomenon, and mean mRSS were lower in the early pattern group insert ignore into journalissuearticles values(p=0.004, p=0.009, and p=0.001, respectively);. The digital ulcer insert ignore into journalissuearticles values(p=0.011); and diffuse cutaneous SSc insert ignore into journalissuearticles values(p=0.016); were more common in the late pattern group. The percentage of pulmonary hypertension insert ignore into journalissuearticles values(p=0.011);, GIS involvement insert ignore into journalissuearticles values(p<0.001);, and arthralgia insert ignore into journalissuearticles values(p=0.027); were higher in the late pattern group. Fatigue insert ignore into journalissuearticles values(p=0.575);, pain insert ignore into journalissuearticles values(p=0.536);, PGA insert ignore into journalissuearticles values(p=0.861);, HAQ insert ignore into journalissuearticles values(p=0.164); and DHI insert ignore into journalissuearticles values(p=0.064); scores were not different between the capillaroscopy pattern groups. Conclusion: Digital ulcer, pulmonary hypertension, and GIS involvement were more common in SSc patients with the late pattern. The fatigue, pain, physical disability, and hand function were similar between capillaroscopy pattern groups.
Keywords : Scleroderma, nailfold capillaroscopy, functional status