The prognostic value of androgenetic alopecia and benign prostatic hyperplasia in men with COVID-19: a prospective multidisciplinaryobservational study of 766 patients from Turkey

Authors : Çağrı TURAN, Nurcan METİN, Türkantuğba YILDIZ, Selcen CAFEROĞLU SKAT, Ahmet CİNİSLİOĞLU, Nazan CİNİSLİOĞLU

Pages : 1518-1528

Doi:10.32322/jhsm.1131546

View : 53 | Download : 13

Publication Date : 2022-10-25

Article Type : Research Paper

Abstract :Objectives: We aimed to investigate the prognostic value of androgenetic alopecia insert ignore into journalissuearticles values(AGA); and benign prostatic hyperplasia insert ignore into journalissuearticles values(BPH); in COVID-19. Material and Method: This prospective study was conducted only on men with COVID-19. All patients were recruited consecutively from the COVID-19 emergency service. 766 patients were evaluated in three independent groups between the ages of 30-49 insert ignore into journalissuearticles values(young);, 50-64 insert ignore into journalissuearticles values(middle-aged);, and 65-75 insert ignore into journalissuearticles values(elderly); to avoid Simson’s paradox. Age, body mass index, smoking, comorbidities, vital signs, oxygen saturation insert ignore into journalissuearticles values(SpO2%);, laboratory insert ignore into journalissuearticles values(CRP, lymphocyte count, ferritin, d-dimer); and computed tomography insert ignore into journalissuearticles values(CT); results, hospitalization insert ignore into journalissuearticles values(primary endpoint);, transfer to intensive care unit insert ignore into journalissuearticles values(ICU);, AGA stage insert ignore into journalissuearticles values(Hamilton-Norwood scale, 3-7=moderate-severe AGA, Gabrin sign); and BPH were recorded. Results: There was no relationship with AGA in any prognostic parameter in the young age group. There was a significant difference in the poor prognostic direction in patients with Gabrin sign, in SpO2 and lymphocyte count for middle-aged, and CRP for the elderly insert ignore into journalissuearticles values(p=0.141, p=0.013, p=0.029; respectively);. The frequencies of transfer to the ICU were higher with no statistical significance in patients with the Gabrin sign. The mortality was more common with no statistical significance in elderly patients with the Gabrin sign. Hospitalization frequencies were significantly higher in patients with BPH in middle-aged and elderly patients insert ignore into journalissuearticles values(p=0.041, p=0.026; respectively);. No relationship was found between transfer to ICU, mortality, and BPH. Conclusions: AGA was not a prognostic indicator, though the increase in hospitalization frequency, particularly in elderly patients with BPH, may be associated with the androgen-mediated COVID-19 severity hypothesis.
Keywords : Androgenetic alopecia, Gabrin sign, benign prostatic hypertrophy, COVID 19, prognosis, hospitalization

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