Analysis of clinical findings and serum micronutrients in pediatric patients with nonalcoholic fatty liver disease

Authors : Meryem KEÇELİ BAŞARAN, Okan GÜRKAN
Pages : 35-39
Doi:10.32322/jhsm.1190206
View : 52 | Download : 13
Publication Date : 2023-01-12
Article Type : Research Paper
Abstract :Aim: Nonalcoholic fatty liver disease insert ignore into journalissuearticles values(NAFLD); is the hepatic finding of systemic lipid and energy metabolism disorder. NAFLD is frequently observed in people with higher body mass index. Serum micronutrient levels play an important role in hepatic metabolism. Material and Method: This study included 60 NAFLD and 66 control patients. . NAFLD and control groups were compared in terms of ultrasonography insert ignore into journalissuearticles values(USG); and shear wave elastography insert ignore into journalissuearticles values(SWE); results. The two groups were compared in serum lipid profile, aminotransferase, insulin, glucose, and HOMA-IR. Both groups were then analyzed in terms of serum ferritin, B12, and vitamin D levels. Results: . 35% insert ignore into journalissuearticles values(n=21); of the patients in the NAFLD group had grade 1, 55% insert ignore into journalissuearticles values(n=33); had grade 2 and 10% insert ignore into journalissuearticles values(n=6); had grade 3 adiposity. HOMA-IR and insulin levels were higher in the NAFLD group insert ignore into journalissuearticles values(p=0.02; p=0.001);. While the serum ferritin level of the patients in the NAFLD group was higher than the control group insert ignore into journalissuearticles values(p=0.001);; the B12 level was lower insert ignore into journalissuearticles values(p=0.006);. In terms of vitamin D, there was no difference insert ignore into journalissuearticles values(p=0.368);. Conclusion: It is essential to identify risk factors in children on follow-up due to NAFLD. USG and liver function tests remain the first option in the diagnosis and screening of NAFLD in children. Serum ferritin, B12, and vitamin D levels of children on follow-up due to NAFLD should be analyzed in consideration of liver fattening.
Keywords : Fatty liver, vitamin, ferritin, elastography

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