Immature granulocyte and other markers in prediction of mortality in spontaneous intracerebral hemorrhage

Authors : İdris KOCATÜRK, Sedat GÜLTEN

Pages : 368-373

Doi:10.32322/jhsm.1225428

View : 25 | Download : 11

Publication Date : 2023-03-27

Article Type : Research Paper

Abstract :Aim: This study aims to evaluate immature granulocyte count insert ignore into journalissuearticles values(IG#); and percentage insert ignore into journalissuearticles values(IG%); in the prediction of mortality in spontaneous intracerebral hemorrhage insert ignore into journalissuearticles values(SICH);. Material and Method: Demographic characteristics and laboratory test results of patients diagnosed with SICH and admitted to the neurology clinic in a tertiary hospital between January 1, 2020, and January 1, 2022, were recorded. One hundred ten patients were included in the study. While 80 of these patients constituted the group that recovered after treatment, 30 of them formed the group that died despite treatment. IG and other laboratory and clinic parameters were statistically compared in both groups. Results: Of 110 patients, 45 insert ignore into journalissuearticles values(42.7%); were female, and 65 insert ignore into journalissuearticles values(57.3%); were male. IG counts were higher in the non-survival group than in the survival group insert ignore into journalissuearticles values(p=0.001);. When the patients were divided according to low IG% insert ignore into journalissuearticles values( =0.6);, 30 patients were in the high IG# group, and 80 patients were in the low IG% group. White blood cell insert ignore into journalissuearticles values(WBC);, neutrophil count insert ignore into journalissuearticles values(NEUT#);, monocyte count insert ignore into journalissuearticles values(MONO#);, IG#, neutrophil-lymphocyte ratio insert ignore into journalissuearticles values(NLR);, and hemorrhage volume insert ignore into journalissuearticles values(HV); values were statistically significantly higher in the high IG% group than in the low IG% group; Glasgow coma score insert ignore into journalissuearticles values(GCS); and percentage of lymphocytes insert ignore into journalissuearticles values(LYMPH%); values were significantly lower too. In addition, the mortality rate in the high IG# group was significantly higher than the mortality rate in the low IG% group insert ignore into journalissuearticles values(53.23% vs. 17.5%);. Conclusion: IG is a new, easily accessible, inexpensive, and promising marker for predicting in-hospital mortality in patients with SICH.
Keywords : Spontaneous intracerebral hemorrhage, inflammation, immature granulocyte, prognosis, mortality