Demographic and clinical characteristics of patients with nonspecific esophageal motility disorder

Authors : İlyas TENLİK, Ömer ÖZTÜRK, Yasemin ÖZDERİN, Ferhat BACAKSIZ, Derya ARI, Orhan COŞKUN

Pages : 608-612

Doi:10.32322/jhsm.1278716

View : 44 | Download : 60

Publication Date : 2023-05-31

Article Type : Research Paper

Abstract :Aim: Although nonspecific esophageal motility disorderinsert ignore into journalissuearticles values(NEMD); is the most common diagnosis in manometry, unlike other primary esophageal disorders, it is the least known and least studied disorder in the literature. Studies with a small number of patient groups have been reported in the literature. The aim of this study is to share the demographic and clinical characteristics of the single center high-volume NEMD patients we have followed up. Material and Method: The study was carried out retrospectively by examining the motility records of 391 patients diagnosed with NEMD in the motility laboratory of the gastroenterology clinic of our hospital. 20-year motility laboratory records between 1991 and 2019 were reviewed. Results: The mean age of 391 patients diagnosed with NEMD was 49.08±14.4 insert ignore into journalissuearticles values(18-90);. 213 insert ignore into journalissuearticles values(54.5%); of them were female, and 178 insert ignore into journalissuearticles values(45.5%); of them were male. The primary symptom was reflux in 56.8% insert ignore into journalissuearticles values(222/391); of the patients, and dysphagia in 43.2% insert ignore into journalissuearticles values(169/391);. While there was no esophagitis in 78.2% of the patients who had endoscopy, esophagitis was found in 21.8% of them. Pathological reflux was detected in 73.5% of the patients whose 24-hour pH was measured. In the repeated manometry results of patients due to increased complaints in their follow-up whose initial manometry findings were compatible with NEMD, 18 patients were diagnosed with achalasia, 5 patients with nutcracker esophagus, and 4 patients with diffuse esophageal spasm insert ignore into journalissuearticles values(DES);. Conclusion: The majority of patients with NEMD are associated with reflux. Patients with NEMD who do not have endoscopic and radiological organic disorders should be re-evaluated with manometry and further examinations if their complaints persist.
Keywords : Nonspecific esophageal motility disorder, esophageal manometry, gastroesophageal reflux