Comparative Evaluation of Antioxidant Capacities of Sage (Salvia spp.) Extracts Using Different Solvents

Authors : Nurdan Gökduman, Şaban Kalay

Pages : 72-79

Doi:10.58854/jicm.1784684

View : 95 | Download : 204

Publication Date : 2025-12-31

Article Type : Research Paper

Abstract :Backround: Growing interest in natural approaches to disease prevention has led to an increased demand for systematic and reliable information in herbal medicine. Oxidative stress has been linked to numerous diseases, and antioxidants are becoming increasingly important in reducing oxidative damage. The genus Salvia, belonging to the Lamiaceae family, is known for its antioxidant properties. In this study, the antioxidant capacities of sage (Salvia spp.), a plant commonly consumed as tea or used as a gargle and also containing endemic species in Anatolia were investigated using different solvents: ethanol, methanol, chloroform, and water. Materials and Methods: The extracts were prepared by maceration, and their antioxidant activities were determined based on the percentage inhibition of the 2,2\\\'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical cation. The primary aim of the study was to identify the extract with the highest antioxidant activity. In addition, the antioxidant capacities of the extracts were compared to butylated hydroxytoluene (BHT), a commonly used synthetic antioxidant. Results: The water, methanol, and ethanol extracts exhibited the highest antioxidant activities, all of which were found to be higher than that of BHT. In contrast, the chloroform extract showed lower antioxidant capacity compared to both the other extracts and BHT. Conclusions: These findings concluded that sage extracts obtained with polar solvents may serve as effective natural antioxidant agents.
Keywords : Adaçayı, Antioksidan aktivite, ABTS, Maserasyon, BHT

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