Antimicrobial activity studies of encapsulated hemp seed oil

Authors : Merve Nur Özdemir, Ertugrul Osman Bursalıoğlu, Derya Doğanay, Ahmet Arif Kurt, İsmail Aslan

Pages : 94-107

Doi:10.58854/jicm.1833182

View : 79 | Download : 238

Publication Date : 2025-12-31

Article Type : Research Paper

Abstract :Objective: In this study, it was aimed to evaluate to what extent the oil obtained from the seeds of the C. sativa plant affects the antimicrobial activity of liposome and liposome-gel formulations that will increase the stabilization, absorption and dispersion effect. Materials and Method: Hemp Seed Oil was used as an antimicrobial agent in our study. C. albicans was investigated as a microorganism. Eight different formulations were prepared from cannabis seed oil and the effect was examined by the spread plate method. Results: The most effective results were observed in the liposomal formulation containing Carbopol® Ultrez 30 compared to the formulation applications and control groups of Cannabis Seed Oil. In a smear sowing study with C. albicans, it was determined that the growth of Cannabis Seed Oil formulations and control groups was limited during one-week examinations. Conlusion: It was determined that the prepared Cannabis Seed Oil formulations had a highly inhibitory effect on the proliferation of C. albicans used in the study. Considering these results, it will lay the groundwork for studies that benefit from Cannabis Seed Oil and C. albicans.
Keywords : Antimikrobiyal Aktivite, Kenevir Tohumu Yağı, Candida albicans, Lipozom, Lipozom- jel

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