Streptococcus pneumoniae acquisition among vaccinated Malaysian hajj pilgrims and its associated factors

Authors : Nabilah İsmail, Nur Adlina Zainuddin, Zakuan Zainy Deris, Zaidah Abdul Rahman, Zeehaida Mohamed, Azian Harun, Siti Suraiya Md Noor, Nyi Nyi Naing, Aniza Abd Aziz, HABSAH HASAN

Pages : 56-62

Doi:10.5799/jmid.vi.328784

View : 8 | Download : 4

Publication Date : 2017-06-01

Article Type : Research Paper

Abstract :Objective: To describe the acquisition of Streptococcus pneumoniae among Malaysian hajj pilgrims and to determine the association with pneumococcal vaccination and respiratory symptoms. Methods: This was a cross sectional study performed on Malaysian hajj pilgrims in a mass ritual gathering event from October to November 2013 in Makkah. Demographic data and associated factors for the respiratory infection were obtained by interview at Kota Bharu airport on their return. A sputum specimen or throat swab was taken from all subjects for S. pneumoniae culture and antimicrobial susceptibility testing. Results: S. pneumoniae was isolated in 1.81% insert ignore into journalissuearticles values(n=10, 95% CI 0.69, 2.93); out of 549 subjects. Fifty percent of them insert ignore into journalissuearticles values(n=5); had received pneumococcal vaccination. Difficulty in breathing was significantly reduced in subjects without S. pneumoniae isolation insert ignore into journalissuearticles values(p =0.042);. In multivariable analysis, the uptake of pneumococcal vaccination was found to be statistically significant in reducing S. pneumoniae acquisition insert ignore into journalissuearticles values(p =0.018); and those at a younger age were more liable to acquire colonization or infection insert ignore into journalissuearticles values(p=0.018);. Runny nose was significantly associated with the vaccinated group insert ignore into journalissuearticles values(p=0.040);. Conclusion: The acquisition of S. pneumoniae among Malaysian hajj pilgrims in 2013 was significantly low with the uptake of pneumococcal vaccination. J Microbiol Infect Dis 2017; 7insert ignore into journalissuearticles values(2);:56-62 
Keywords : Streptococcus pneumoniae, vaccinated, Malaysian, hajj pilgrims, associated factors