Epidemiology of Candida colonization in medical surgical intensive care unit of a tertiary care teaching hospital of North India

Authors : Afzal AZİM, Armin AHMED, Arvind Kumar BARONİA, Reema YADAV, Preeti SHARMA, Rungmei S K MARAK

Pages : 147-152

Doi:10.5799/jmid.493851

View : 48 | Download : 5

Publication Date : 2018-12-15

Article Type : Research Paper

Abstract :Objective: Invasive candidiasis is associated with increased morbidity and mortality in critically ill patients. Current study was undertaken to study the colonization trend in critically ill patients admitted to a medical /surgical ICU of a tertiary care teaching hospital. Methodology: Data for the current study has been derived from a larger database generated for external validation of risk prediction scores for invasive candidiasis conducted in a 12 bedded medical/surgical ICU of a tertiary care hospital of North India. Non neutropenic adult patients with >48 hours of ICU stay were included in the study. Colonization surveillance samples were collected from oral cavity, endotracheal aspirates, axilla, perineum and urine at the time of admission and then on 3 rd , 7 th , 14 th and 21 st day of ICU stay. Blood culture samples were taken at admission and then as per physician’s discretion. Results: Total 200 patients were enrolled from July 2013 to November 2014. Ninety five percent patients were colonized with Candida either at admission or during their stay in ICU. The most common species responsible for colonization was Candida glabrata insert ignore into journalissuearticles values(27%); followed by C. tropicalis insert ignore into journalissuearticles values(20.5%); and C. auris insert ignore into journalissuearticles values(18%);. Seventeen patients developed Candida blood stream infection. C. tropicalis was the most common species causing candidemia. C.auris was most frequent colonizer of axilla insert ignore into journalissuearticles values(54.2%);, while rectal swabs had high growth of C. glabrata insert ignore into journalissuearticles values(44.9%);. Conclusion: Our study population had high rate of Candida colonization. C. glabrata was the most common colonizer followed by C. tropicalis .   J Microbiol Infect Dis 2018; 8insert ignore into journalissuearticles values(4);:147-152.
Keywords : Candida auri, Candida colonization, Candida glabrata, Candida tropicalis, critically ill

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