Pattern of Surgical Antibiotic Prophylaxis for Surgical Site Infections in at two Teaching Hospitals, Islamabad, Pakistan

Authors : Zakir KHAN, Naveed AHMED, Asimur REHMAN, Faiz Ullah KHAN, Hazir RAHMAN

Pages : 104-111

Doi:10.5799/jmid.614180

View : 8 | Download : 5

Publication Date : 2019-09-15

Article Type : Research Paper

Abstract :Objectives: To investigate the utilization pattern of Surgical antibiotic prophylaxis insert ignore into journalissuearticles values(SAP); for the prevention of surgical infections in most common abdominal and orthopedic surgical procedures. Methods : A prospective observational and non-intervention study was conducted at two teaching hospitals insert ignore into journalissuearticles values(PIMS and SIH); in Islamabad, Pakistan. Prescriptions records were reviewed to assess the utilization pattern of SAP during the nine-month duration. Data regarding most common surgical procedures, antimicrobial utilization, dose, route and administration timing of SAP were extracted for analysis. Observed practices were compared with standard treatment guidelines. Results : Out of total 1512 surgical procedures about, 56.9% insert ignore into journalissuearticles values(n=860); of patients performed abdominal followed by 652 insert ignore into journalissuearticles values(43.1%); orthopedic surgical procedures. A total of 212 insert ignore into journalissuearticles values(14%); surgical procedures were completely correct in all steps. SAP were given in 1474 insert ignore into journalissuearticles values(97.5%); of surgical procedures. In 712 of the participants insert ignore into journalissuearticles values(48.3%); were given Ceftriaxone following by Cefazolin insert ignore into journalissuearticles values(n=247, 16.7%);. Abdominal surgeries were majorly managed with Ceftriaxone insert ignore into journalissuearticles values(59%); while the orthopedic surgeries managed with Ceftriaxone insert ignore into journalissuearticles values(31.3%); and Cefazolin insert ignore into journalissuearticles values(30%);. Appropriate choice of SAP was observed in insert ignore into journalissuearticles values(n=275; 18.6%); procedures and about half insert ignore into journalissuearticles values(n=719, 49%); received antibiotics within optimal timing. The appropriate choice/selection of SAP according to the guidelines was greater in orthopedic surgical procedures insert ignore into journalissuearticles values(n=212; 14.8%); than abdominal surgeries insert ignore into journalissuearticles values(n=63; 4.3%);; p≤0.001. Compliance with respect to timing was significantly lower in an orthopedic surgical procedure insert ignore into journalissuearticles values(n=301); as compared to abdominal surgeries insert ignore into journalissuearticles values(n=418);; p≤0.001. Similarly, a statistically significant difference observed between PIMS and SIH with respect to SAP practices; p≤0.001. Conclusions : Inappropriate choice, the timing of administration and combination of SAP were observed in the current study. J Microbiol Infect Dis 2019; 9insert ignore into journalissuearticles values(3);:104-111.
Keywords : Surgery, perioperative, antibiotic, prophylaxis, hospital