Clinical Manifestation and Characteristics of COVID-19 in Pregnants: A Retrospective, Single-Center Study

Authors : Esmeray MUTLU YILMAZ, Eda KOKSAL, Gökhan UNVER, Sercan SERİN

Pages : 38-46

Doi:10.5799/jmid.1130058

View : 13 | Download : 2

Publication Date : 2022-06-15

Article Type : Research Paper

Abstract :Objectives: Along with the COVID-19 pandemic, pregnant women have experienced COVID-19 symptoms of varying severity. Therefore, we aimed to show the clinical, laboratory, and radiological findings for three different trimesters in pregnant women diagnosed with COVID-19. Methods: All hospitalized pregnant women with positive SARS-CoV-2 nucleic acid tests were included in this study. The severity of the disease was classified using the NIH Classification of Severity of Disease. Results: None of the 206 participants were vaccinated. The number of asymptomatic or presymptomatic patients, those with mild, moderate, and severe disease, was 73insert ignore into journalissuearticles values(35.4%);, 59insert ignore into journalissuearticles values(28.6%);, 68 insert ignore into journalissuearticles values(33.1%);, and 6 insert ignore into journalissuearticles values(2.9%);, respectively. The gestational age of symptomatic patients was lower than that of asymptomatic patients insert ignore into journalissuearticles values(29 vs. 37 weeks); insert ignore into journalissuearticles values(p= 0.001);. The incidence of pneumonia increased with the trimester of pregnancy increased insert ignore into journalissuearticles values(p<0.001);. Sixty-six of the pregnancies insert ignore into journalissuearticles values(32.0%); ended with term births, and 11 insert ignore into journalissuearticles values(0.5%); gave premature birth. Three pregnancies resulted in miscarriage insert ignore into journalissuearticles values(1.4%);, and oneinsert ignore into journalissuearticles values(0.4%); resulted in intrauterine fetal death. Of the preterm deliveries, nineinsert ignore into journalissuearticles values(64.3%); had pneumonia. There was no significant relationship between the disease severity and delivery time insert ignore into journalissuearticles values(p=0.075);, but a significant relationship between the disease severity and the delivery mode. Expected vaginal delivery occurred in 18 asymptomatic patients insert ignore into journalissuearticles values(72%);, whereas cesarian/section was performed in 75.6% insert ignore into journalissuearticles values(n=31); of symptomatic patients insert ignore into journalissuearticles values(p<0.001);. Conclusion: This study reflects the natural course of COVID-19 since our patients were not vaccinated. We think the results will be better with the increase in vaccination rates.
Keywords : Pregnancy, COVID 19, Pandemic, Pneumonia