The role of the systemic inflammatory response index in the prediction of chronic total occlusion: useful or not?

Authors : Gökhan Ergün, Yasemin Doğan

Pages : 542-546

Doi:10.47582/jompac.1349803

View : 64 | Download : 85

Publication Date : 2023-10-27

Article Type : Research Paper

Abstract :Aim: Inflammation is very important in the pathogenesis of atherosclerosis and CAD. Chronic total occlusion (CTO) is a chronic form of CAD and is common in patients with severe CAD. The aim of this study was to determine the association of the systemic inflammatory response index (SIRI), a marker of inflammation, with CTO. Materials and Methods: Our study was retrospective and included 100 CAD patients with CTO and 100 CAD patients without CTO. SIRI was compared between the two groups. Results: Among the basic clinical and laboratory characteristics of the patients, age, white blood cell, and neutrophil counts were statistically higher in the CTO group (p=0.044, p=0.044, p=0.036, respectively). SIRI parameters were similar between the groups, and no statistical difference was observed (p=0.111). According to the ROC analysis, the optimum cut-off value for SIRI was >1040 (sensitivity 70.0% and specificity 44.0%). Conclusion: SIRI is not a useful predictor for the detection of CTO.
Keywords : Sistemik inflamatuar yanıt indeks, kronik total oklüzyon, koroner arter hastalığı