The diagnosis and treatment of idiopathic pulmonary fibrosis

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Journal of Medicine and Palliative Care
Volume:5 Issue:1
The diagnosis and treatment of idiopathic pulmonary fibrosis

The diagnosis and treatment of idiopathic pulmonary fibrosis

Authors : Berna Akıncı Özyürek

Pages : 85-90

Doi:10.47582/jompac.1418227

View : 94 | Download : 139

Publication Date : 2024-02-29

Article Type : Review Paper

Abstract :Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrosing interstitial lung disease (ILD) of unknown cause. The prognosis of IPF is poor, respiratory failure is the most common cause of mortality. Velcro rales are typical on respiratory system examination. Clubbing is seen in 30-60% of IPF cases. There is no laboratory test specific to IPF. Usual interstitial pneumonia (UIP) pattern is seen in IPF. UIP features in high-resolution computed tomography (HRCT); peripheral subpleural bibasilar reticular opacities, honeycombing, traction bronchiectasis and interseptal thickening. It shows craniocaudal localization. Diagnosis of IPF; It is diagnosed by the combination of HRCT findings and clinical findings. Antifibrotic drugs (Pirfenidone and Nintedanib) slow down the progression of IPF and reduce the number of annual attacks and reduce the frequency of hospitalization.
Keywords : idiyopatik pulmoner fibrozis, olağan interstisyel pnömoni, antifibrotik tedavi

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