Evaluation of hemogram parameters in the diagnosis of ectopic pregnancy, early pregnancy loss and threatened miscarriage

Authors : İsa Temur

Pages : 207-212

View : 18 | Download : 8

Publication Date : 2025-06-18

Article Type : Research Paper

Abstract :Aims: In present study, it aimed to analyse the importance and potential use of inflammatory blood parameters in the prediction of threatened miscarriage (TM), early pregnancy loss (EPL) and ectopic pregnancy (EP). Methods: Between October 2021 and 2023, the demographic data and obstetric histories of a total of 300 patients (n=100 for each group) diagnosed with TM, EPL, and EP at a single center, as well as 100 healthy women with a first-trimester intrauterine pregnancy, were analyzed. Complete blood count data obtained from these participants included. In statistical analyses, the significance level was set at p<0.05. Results: Although there was no notable discrepancy between the groups with regard to age, gravidity, and gestational week, the EPL cohort exhibited a markedly elevated parity rate (p=0.003). Additionally, notable disparities in platelet-lymphocyte ratio (PLR) were observed between the EPL and TM groups (p=0.021) and between the EP and TM groups (p=0.030). Additionally, monocyte-lymphocyte ratio (MLR) and neutrophil-lymphocyte ratio (NLR) were found to be higher in the EP group compared to the TM and EPL groups (p=0.004 and p=0.001 for MLR; p=0.000 in both comparisons for NLR). Conclusion: Inflammatory blood parameters namely PLR, MLR, and NLR appear to be significant biomarkers for the diagnosis and management of TM, EPL, and EP. These findings suggest that integrating PLR, MLR, and NLR into obstetric practice could facilitate the early diagnosis and treatment of these complications.
Keywords : Düşük tehdidi, erken gebelik kaybı, ektopik gebelik, inflamasyon, hematolojik belirteçler

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