Constipation after Botulinum Toxin- an Injection in Lower and Upper Limb Muscles:

Authors : Georges F Vles, Johan S Vles, Catherine G Faber, Mieke C Hermans, Juan D Martina, Anton de Louw

Pages : 47-51

Doi:10.5835/jecm.v26i1.425

View : 53 | Download : 13

Publication Date : 2010-12-06

Article Type : Other Papers

Abstract :We report three patients who developed transient constipation after receiving therapeutic doses of Botulinum Toxin-A insert ignore into journalissuearticles values(BTX-A); for spasticity of the lower limbs insert ignore into journalissuearticles values(two cases); and the upper limb insert ignore into journalissuearticles values(one case);. Constipation was observed within the first week after treatment. In all three cases, this symptom resolved completely almost simultaneously with disappearance of the therapeutic effects of BTX-A on mobility. None of the patients had previously received BTX-A injections. Two patients received a second treatment and both presented the same autonomic cholinergic remote symptoms. The third patient refused a second treatment due to the complication noted earlier. Familiarity with this autonomic systemic side effect of BTX-A is essential for those who treat patients already at risk for gastro-intestinal dysfunction. Because the adverse effects were treatable and transitory, we believe that constipation per se is not an absolute contra-indication, if from a therapeutic point of view view, BTX-A is indicated.
Keywords :

ORIGINAL ARTICLE URL