Erişkin Enürezis Nokturnada İmipramin Ve Dezmopresin (Ddavp) İle Uzun Süreli Tedavi Sonuçlarının Karşılaştırılması

Authors : R AŞÇI, Ş SARIKAYA, R BÜYÜKALPELLİ, Af YILMAZ, S YILDIZ

Pages : 0-0

Doi:10.5835/jecm.v14i1.738

View : 39 | Download : 47

Publication Date : 2009-12-23

Article Type : Other Papers

Abstract :The Comparison of Imipramine and Desmopressin insert ignore into journalissuearticles values(DDAVP); Long-Term Therapy Results in Adult Enuresis Nocturna The long-term therapy results of Imipramine and Desmopressin were compared in 35 adult patients with monosymptomatic enuresis nocturna. Randomly selected 17 patients were treated with 1 mg/kg oral Imipramine and 18 with 20 pg intranasal Desmopressin nightly for three months. Dose titration was done for Desmopressin monthly. Complete improvoment rates in the Desmopressin group were 55%, 61% and 72% after the first, the second and the third months respectively, whereas in the Imipramine group these were found 23%, 40% and 47 %, respectively. The difference between the improvement rates of two groups were not statistically significant insert ignore into journalissuearticles values(p>0.05);. Three months after the end of therapy, complete improvement rates were 30% and 28% for Desmopressin and Imipramine respectively. Relaps rates were 61% in the Desmopressin group and 30% in the Imipramine group insert ignore into journalissuearticles values(p 0.05);. Tedavi kesildikten 3 ay sonra tam iyileşme oranlan dezmopressin için %30 ve imipramin için %28 bulundu. Rölaps oranlan ise dezmopressin için %61 ve imipramin için %30 idi insert ignore into journalissuearticles values(p<0.05);. İlaçlara bağlı ciddi yan etki saptanmadı. Rölaps oranı dezmopressin grubunda yüksek olmasına rağmen erişkin enürezis nokturnanın uzun süreli tedavisinde iki ilaç arasında fark bulunamadı.
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