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  • Journal of Experimental and Clinical Medicine
  • Volume:16 Issue:2
  • Perinatal Asphyxia And Thrombocytopenia

Perinatal Asphyxia And Thrombocytopenia

Authors : N BELET, Ş KÜÇÜKÖDÜK, R SANCAK, S UYSAL
Pages : 0-0
Doi:10.5835/jecm.v16i2.721
View : 112 | Download : 12
Publication Date : 2009-12-23
Article Type : Other Papers
Abstract :In this study, thrombocytopenia incidence and the mechanism responsible for the thrombocytopenia in asphyxiated infants were investigated within 2 weeks of life. We studied 24 full-term newborn infants with asphyxia and 10 term healthy newborns. Thrombocytopenia developed in 25% of the infants in 0-2 days, 36.8% in 3-6 days and 26.6% in 7-14 days after birth. The mortality ratio in perinatal asphyxia was 29.1% and only one patient had thrombocytopenia. Although the mean platelet volume values of asphyxiated-thrombocytopenic patients were higher than those of the asphyxiated-nonthrombocytopenic patients, no statistical difference was found. We couldn`t find any effect of the thrombocytopenia on mortality in perinatal asphyxia. Moreover, the severity of hypoxic ischemic encephalopathy didn`t show any relation with platelet count. Perinatal Asfiksi ve Trombositopeni Bu çalışmada asfiktfk term yenidoğanlarda hayatın ilk iki haftası içinde trombositopeni insidansı ve trombositopeniden sorumlu mekanizma araştınldı. 24 asfiksili bebek ve 10 sağlıklı bebek çalışıldı. Asfiktik bebeklerde hayatın ilk iki günü içinde %25.0, 3-6. günlerde %36.8 ve 7-14. günlerde %26.6 oranında trombositopeni gelişti. Perinatal asfiksili infantlarda mortalité oranı %29.1`di ve yalnızca bir hastada trombositopeni vardı. Bu çalışmada perinatal asfikside trombositopeninin mortalité üzerine etkisi bulunamadı. Asfiktik trombositopenik hastaların ortalama trombosit volümü asfiktik nont-rombositopenik bebeklerden yüksek olmasına rağmen istatistiksel fark gözlenmedi. Aynca hipoksik-iskemik ensefalopati şiddeti trombosit sayısıyla ilişkili değildi.
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