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  • Journal of Experimental and Clinical Medicine
  • Volume:19 Issue:1
  • The Acanthosis Nigricans Associated With Gastric Adenocarcinoma And Neurofibromatosis

The Acanthosis Nigricans Associated With Gastric Adenocarcinoma And Neurofibromatosis

Authors : T CANTÜRK, L YILDIZ, A YILDIZ, O AYDIN, Ay TURANLI
Pages : 0-0
Doi:10.5835/jecm.v19i1.262
View : 46 | Download : 8
Publication Date : 2009-12-23
Article Type : Other Papers
Abstract :We presen Led a case of acanthosis nigricans who exhibited an internal malignancy and neurofibromatosis. The patienl who is 45 years old had pruritus and axillary and inguinal discoloration resembling Acanthosis nigricans. The diagnosis was confirmed bv the biopsy of the skin. The tomographic, endoscopic, and histopathologic singular revealed a poorly differentiated gastric carcinoma of the corpus which was at advanced stage. There were macules in close similarity with cafe an lait. macules, and skin-colored, pedunculated soft nodules. The histopathologic diagnosis of neurofibroma was confirmed by the excision of one of the nodules. Akantozis Nigrikans ile Birlikte Gastrik Adenokarsinom ve Nörofibromatozis interna! malignite ve nörofibromatozis ile. birlikte akantozis nigrikans olgusunu sunuyoruz. Kaşıntı ve akantozis nigrikansı çağrıştıran aksiller ve inguinal diskolorasyon yakınmaları ile başvuran 45 yaşındaki erkek hastada tanı deri biyopsisi ile doğrulandı. Tomografik. endoskopik ve hisLopatolojik araştırmalarda mide korpusunda ileri evrede, az diferansiye adenokarsinom saptandı.Gövdede `cafe an lait.` lekeleri ve deri renginde, pedinküle yumuşak nodüller mevcuttu. Histopatolojik olarak nörofibrom tanısı nodüllerin birinin eksizyonu ile doğrulandı.
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