Recent microwave research studies of Gazi Biophysics & Gazi Non-Ionizing Radiation Protection Center

Authors : Nesrin SEYHAN

Pages : 271-272

Doi:10.5835/jecm.omu.30.03.017

View : 50 | Download : 8

Publication Date : 2013-11-05

Article Type : Other Papers

Abstract :Gazi Biophysics is located in Ankara at the Medical Faculty of Gazi University and has been carrying out in vivo and in vitro research studies on the biological impacts of Static, Extremely Low Frequency insert ignore into journalissuearticles values(ELF); and Microwave insert ignore into journalissuearticles values(MW); electromagnetic fields insert ignore into journalissuearticles values(EMF); since 1989. Our laboratory includes: Physicists, biologists, electrical engineers, all of whom are studying how living systems respond to EMF. Our research team includes physicists, biologists, electrical engineers, physicians, biochemists, pathologists and veterinarians.Gazi Biophysics is Academic Representative to NATO Science and Tecnology Organisation insert ignore into journalissuearticles values(NATO STO HFM); since 2007, International Advisory Committee member of EMF and Health to WHO since 2001, and Scientific Secreteriat Member of International Commission for Electromagnetic Safety insert ignore into journalissuearticles values(ICEMS); since 2007. We do expose animals and cell cultures to Radiofrequency insert ignore into journalissuearticles values(RF); EMF including mobile phones and we do clinical research. We also measure all kinds of EMF sources between 5 Hz-60 GHz, including cellular phones, base stations, transformers, high power lines, TV and radio antennas, Microwave ovens, Diathermy units, Wi-Fi’s. Magnetic resonance imaging insert ignore into journalissuearticles values(MRI);’s, Radars under Gazi Nonionizing Radiation Protection Center insert ignore into journalissuearticles values(GNRK);. GNRK has been founded by Gazi Biophysics in July, 2004. Gazi Biophysics & GNRK have 70 published articles related with biological effects of EMF. Below, I will present only the results of our recent MW research studies. These studies include Pregnancy Study, DNA Study, Thyroid Study, Oxidative Stress Study, Blood Lymphocytes Study, Mitochondrial Membrane Potential of Breast Fibroblast cells and Breast Cancer insert ignore into journalissuearticles values(MCF- 7); cells Study. Pregnancy studyinsert ignore into journalissuearticles values( 2007-cont.); insert ignore into journalissuearticles values(in vivo);: In this study, adult, pregnant, newborn and offspring White New Zealand rabbits were exposed to 1800 MHz GSM modulated RFR insert ignore into journalissuearticles values(217 Hz, 20dBm, 14V/m); for 7 days, 15 min/day. We found increased DNA base modification and free radical formation in brain tissue of non-pregnant adults, increased oxidative stress in liver tissue of non pregnant adults, pregnants and 2 days old newborns increased apoptotic cells in the brain insert ignore into journalissuearticles values(neurons, glial cells); and eye insert ignore into journalissuearticles values(cornea, lens); tissues of adults, pregnants and newborns increased DNA base modification in liver tissue of female, infants insert ignore into journalissuearticles values(one month old);. There has been 10 published articles on the Pregnancy Study. DNA study insert ignore into journalissuearticles values(clinical);: In this study, 6 women, 2 men insert ignore into journalissuearticles values(30-47 years old); were exposed to 900 MHz GSM Modulated RFR 217 Hz, 577 μs, from an Apple iPhone cupertino, CA mobile phone, with SAR 0.974 W/kg. Human hairs are plucked within 6cm x 6cm area behind the right ear before and after using 15 min and 30 min phone call. Modified Comet Assay Technique is used for DNA analysis of the hair root cells.We found significantly increased Single-strand DNA breaks in the hair root cells after using 15 minutes and 30 minutes cellular phone exposure. Thyroid study insert ignore into journalissuearticles values(in vivo);: In this study, 2 months old Wistar rats were exposed to 900 MHz GSM Modulated RFR insert ignore into journalissuearticles values(217 Hz, 1.35 W/kg); for 21 days, 15min/day. We found induced hypothyroidism and caspase activation insert ignore into journalissuearticles values(indicator of apoptosis);. Oxidative stress study insert ignore into journalissuearticles values(in vivo);: In this study, 2 months old Wistar rats were exposed to 900 MHz GSM Modulated RFR insert ignore into journalissuearticles values(217 Hz, 1.35 W/kg); for 21 days, 15min/day. We found oxidative damage in liver, heart, lung and testis tissues. Blood lymphocytes study insert ignore into journalissuearticles values(in vitro);: In this study, humanperipheral blood lymphocyte cells were exposed to 1800 MHz GSM Modulated RFR insert ignore into journalissuearticles values(217 Hz, 0.21 W/kg); for 6, 8, 24 and 48 h. We found inhibited cell proliferation, increased Sister Chromatid Exchange frequency insert ignore into journalissuearticles values(indicator of DNA damage); Mitochondrial membrane potential of breast fibroblast cells and breast cancer insert ignore into journalissuearticles values(MEF-7); cells studies insert ignore into journalissuearticles values(in vitro);: In these studies, Breast Fibroblast and MCF-7 cells were exposed to 2.1 GHz MW for 4 h and 24 h. We found decreased viability of Breast Fibroblast and MCF-7 cells, increased apoptotic activities of Breast Fibroblast and MCF-7 cells, decreased Mitochondrial Membrane Potential insert ignore into journalissuearticles values(ΔΨm); in Breast Fibroblast cells, increased Mitochondrial Membrane Potential insert ignore into journalissuearticles values(ΔΨm); and cytochrome-c level in MCF-7 cells. Endocrinology study insert ignore into journalissuearticles values(in vivo);: In this study, rats were exposed to 1800 & 2100 MHz RFR for 1 or 2 months.We found decreased melanocyte-stimulating hormone levelinsert ignore into journalissuearticles values(MSH); and delay on the satiety feeling. Skin hydroxyproline study insert ignore into journalissuearticles values(in vivo);: Two months old male wistar rats were exposed to 900-MHz pulse modulated RFR at an average whole body SAR of 1.35 W/kg for 3 weeks, for 20 min/day. Skin insert ignore into journalissuearticles values(abdominal costa); hydroxyproline level analyzed with LC/MS MS technique. We found significantly increased in skin hydroxyproline level. Ongoing studies: Effect of multi-frequency EMF insert ignore into journalissuearticles values(50 Hz&2100 MHz); on the permeability of blood brain barrier of non diabetic&diabetic rats. Effects of chronic RFR exposure on the organs of female and male rats with melatonin injection. 2100 MHz RFR exposure leads structural changes on the genital ducts of male rats insert ignore into journalissuearticles values(completed, not published yet);. Evaluation of reactive oxygen species insert ignore into journalissuearticles values(ROS); production and antioxidant properties of black, green, sage and roseship tea by spin trapping electron spin resonance insert ignore into journalissuearticles values(ESR); spectroscopy in normal and malignant lymphocytes exposed to UV radiation.
Keywords : Blood lymphocytes, breast cancer mcf 7, cells, endocrinology, radiofrequency

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