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  • Journal of Experimental and Clinical Medicine
  • Volume:32 Issue:3
  • Sorafenib-induced pancreatitis

Sorafenib-induced pancreatitis

Authors : Talat AYYILDIZ, Taner AYDIN, Ahmet Tarık EMİNLER, Çınar YILDIRIM, Kader IRAK, Murat KIYICI, Selim GÜREL, Selim Giray NAK, Macit GÜLTEN, Enver DOLAR
Pages : 133-135
View : 43 | Download : 11
Publication Date : 2015-11-17
Article Type : Research Paper
Abstract :Sorafenib is an inhibitor of multikinase proteins which is used for metastatic renal cell carcinoma and advanced stage hepatocellular carcinoma. Its side effects include serum amylase and lipase elevations anticipated to occur within first weeks of treatment but clinically and radiologically evident acute pancreatitis develops rarely. Five cases of acute pancreatitis have been reported in literature until date. The case we described here is the sixth case of clinically diagnosed acute pancreatitis. 
Keywords : Hepatocellular carcinoma, Pancreatitis, Sorafenib, Tyrosine kinase inhibitor

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